Understanding the chemical nature and synthesis of key compounds is fundamental for both producers and users in the chemical industry. 4-Aminopyridine (CAS 504-24-5) is a compound whose synthesis and properties are of significant interest, particularly for its role as a pharmaceutical intermediate and research chemical. As a seasoned manufacturer of fine chemicals in China, we offer an overview of its essential characteristics and production.

4-Aminopyridine is characterized by its pyridine ring substituted with an amino group at the 4-position. Its chemical formula is C5H6N2, and it exhibits a molecular weight of 94.11 g/mol. Key physical properties include its appearance as an off-white to tan solid, a melting point typically between 157-160°C, and solubility in water. Chemically, the presence of the amino group and the nitrogen in the pyridine ring contributes to its reactivity, making it a versatile building block in organic synthesis. Its role as a potassium channel blocker is a critical aspect of its biological activity, driving its use in pharmaceutical research.

The synthesis of 4-Aminopyridine typically involves several routes. One common method is the amination of 4-chloropyridine or 4-bromopyridine. Another established pathway involves the Chichibabin reaction, where pyridine is directly aminated using sodium amide. The efficiency and purity of the final product depend heavily on the reaction conditions, catalysts, and purification techniques employed. As a manufacturer, optimizing these synthetic routes to achieve high yield and purity, while also ensuring cost-effectiveness, is a continuous focus.

Quality control is paramount in the production of 4-Aminopyridine. Manufacturers must employ rigorous analytical methods to verify the compound's identity, purity, and the absence of undesirable byproducts. Techniques such as Gas Chromatography (GC), High-Performance Liquid Chromatography (HPLC), and Nuclear Magnetic Resonance (NMR) spectroscopy are standard for assessing purity and confirming the structure. We implement comprehensive quality assurance measures throughout our manufacturing process, from raw material sourcing to final product inspection, to ensure our 4-aminopyridine meets the highest industry standards.

For businesses looking to purchase 4-Aminopyridine, partnering with a reliable China-based manufacturer like ourselves provides access to high-quality products manufactured with robust synthetic expertise and stringent quality control. We are dedicated to supplying this essential chemical to meet the diverse needs of the pharmaceutical and research sectors.