For chemists and researchers in organic synthesis, understanding the fundamental properties and synthesis routes of key intermediates is critical for efficient laboratory work and industrial production. This article focuses on 4-Chlorobenzamidine Hydrochloride (CAS: 14401-51-5), detailing its chemical nature and how it is typically synthesized. NINGBO INNO PHARMCHEM CO.,LTD. provides this compound to researchers and manufacturers who need to buy high-quality chemical building blocks.

Chemical Profile of 4-Chlorobenzamidine Hydrochloride

4-Chlorobenzamidine Hydrochloride is characterized by its chemical structure, which includes a benzene ring substituted with a chlorine atom at the para position and an amidine group attached to the ring. Its IUPAC name is 4-chlorobenzenecarboximidamide hydrochloride. The compound typically appears as a white to off-white crystalline powder, with a purity often specified at 98% by High-Performance Liquid Chromatography (HPLC). Its molecular formula, C7H8Cl2N2, and molecular weight of approximately 191.06 g/mol are standard identifiers. The hydrochloride salt form enhances its stability and solubility in polar solvents, making it easier to handle in synthesis processes. For those looking to purchase this compound, understanding these specifications ensures you receive the correct material for your needs.

Synthesis Pathways and Industrial Production

The synthesis of 4-Chlorobenzamidine Hydrochloride commonly starts from p-chlorobenzonitrile. A typical method involves reacting p-chlorobenzonitrile with a strong base, such as lithium bis(trimethylsilyl)amide (LiHMDS), in an anhydrous solvent like tetrahydrofuran (THF). This reaction forms an intermediate that is subsequently treated with hydrochloric acid (HCl), often in an alcoholic solvent, to precipitate the desired hydrochloride salt. The crude product is then filtered, washed, and dried. The yield and purity are influenced by reaction conditions, solvent choice, and purification techniques. Manufacturers like NINGBO INNO PHARMCHEM employ optimized protocols to ensure consistent production of high-purity 4-Chlorobenzamidine Hydrochloride, making it readily available for those seeking to buy this essential chemical.

Sourcing and Quality Assurance

When you need to source 4-Chlorobenzamidine Hydrochloride, partnering with a reputable chemical supplier is essential. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier from China, committed to delivering products that meet stringent quality standards. We provide detailed product specifications, including purity data and CAS numbers, to aid your purchasing decisions. Our efficient supply chain ensures timely delivery, whether you require small quantities for research or bulk orders for industrial production. We encourage prospective buyers to inquire about our pricing and to request samples to verify the quality and suitability of our 4-Chlorobenzamidine Hydrochloride for their specific applications.

By understanding the chemical properties and synthesis of 4-Chlorobenzamidine Hydrochloride, researchers and manufacturers can better leverage its potential. NINGBO INNO PHARMCHEM is your trusted partner for sourcing this vital intermediate, ensuring quality and reliability in every order. Contact us today to discuss your requirements and how we can support your chemical synthesis endeavors.