For chemists and formulators, understanding the intrinsic chemical properties of raw materials is fundamental to successful synthesis and product development. 2',6'-Dihydroxyacetophenone (CAS 699-83-2) is a compound that offers a unique combination of reactivity and stability, making it a valuable asset in various chemical processes. This article explores its key properties and diverse applications, highlighting why it's a sought-after intermediate for manufacturers globally.

Key Chemical Properties of 2',6'-Dihydroxyacetophenone

2',6'-Dihydroxyacetophenone, with its molecular formula C8H8O3 and molecular weight of 152.15, is characterized by the presence of two phenolic hydroxyl groups and a ketone functional group. These features impart specific reactivity, allowing it to participate in a range of organic reactions such as esterification, etherification, and condensation. The compound is typically supplied as a yellowish-beige powder, with a reported melting point often in the range of 155-158 °C. While sparingly soluble in water, it exhibits better solubility in common organic solvents, facilitating its use in various reaction media. The purity level of ≥99% available from reputable suppliers is critical for ensuring predictable reaction outcomes.

Synthesis Applications and Versatility

The inherent reactivity of 2',6'-Dihydroxyacetophenone makes it a crucial intermediate in several branches of chemical synthesis:

  • Pharmaceutical Intermediates: Its primary application is as a building block for Active Pharmaceutical Ingredients (APIs). The hydroxyl groups can be readily functionalized, and the acetyl group can undergo various transformations, leading to the synthesis of complex drug molecules. Researchers looking to buy 2',6'-dihydroxyacetophenone for novel drug discovery often rely on its structural versatility.
  • Fine Chemical Production: Beyond pharmaceuticals, this compound finds use in the broader fine chemical industry. It can be a precursor for specialty chemicals, agrochemical intermediates, or materials with specific optical or electronic properties.
  • Research and Development: In academic and industrial R&D labs, 2',6'-Dihydroxyacetophenone is used as a model compound for studying reaction mechanisms or as a starting material for synthesizing novel organic compounds. A consistent supply from a trusted manufacturer ensures that research projects are not hampered by material shortages.

Procurement and Supply Chain Considerations

When seeking to purchase 2',6'-dihydroxyacetophenone, it is essential to engage with a reliable manufacturer or supplier. Companies operating in China, such as NINGBO INNO PHARMCHEM CO.,LTD., are well-positioned to provide this intermediate with high purity and competitive pricing. Procurement managers should prioritize suppliers who can offer consistent quality, timely delivery, and transparent documentation, including Certificates of Analysis. Understanding the CAS number (699-83-2) is key for accurate sourcing and communication with vendors.

The availability of 2',6'-dihydroxyacetophenone at competitive prices from established suppliers in China makes it an accessible and valuable component for many advanced chemical manufacturing processes. By leveraging the expertise of these manufacturers, businesses can secure the materials needed for innovation and production.