The Chemical Properties and Synthesis Applications of 3-Formylpicolinic Acid
3-Formylpicolinic Acid (CAS 19182-29-7) is a fascinating molecule with significant utility in organic synthesis, particularly as a versatile intermediate in the pharmaceutical and fine chemical industries. Understanding its chemical properties is key to unlocking its full potential in various research and development (R&D) and manufacturing processes. This article delves into these properties and its prominent synthesis applications.
Key Chemical Properties of 3-Formylpicolinic Acid
As a fine chemical intermediate, 3-Formylpicolinic Acid exhibits several defining characteristics:
* Appearance: Typically, this compound presents as a light yellow to brown solid. This physical state is common for many organic acid derivatives and is a crucial identifier for procurement professionals when they buy the material.
* Melting Point: The melting point of 3-Formylpicolinic Acid is approximately 156-158°C. This precise range is a strong indicator of its purity and crystalline structure, vital information for scientists and formulation chemists.
* Molecular Formula and Weight: With a molecular formula of C7H5NO3 and a molecular weight of 151.12 g/mol, it is relatively lightweight and easily handled in laboratory settings. These fundamental properties are essential for stoichiometric calculations in synthesis.
* Acidity: The presence of a carboxylic acid group (-COOH) lends acidic properties to the molecule, with a predicted pKa of around 4.01. This acidity influences its reactivity and solubility, making it suitable for reactions in specific pH environments.
* Reactivity: The molecule contains two key functional groups: an aldehyde (-CHO) and a carboxylic acid (-COOH). The aldehyde group is highly reactive, participating in nucleophilic addition reactions, condensations, and oxidations. The carboxylic acid group can undergo esterification, amidation, and decarboxylation. This dual functionality makes it a powerful synthon.
Synthesis Applications in Industry
The unique structural features of 3-Formylpicolinic Acid enable its use in a wide array of synthetic pathways:
* Pharmaceutical Synthesis: It is a critical building block for numerous APIs. For instance, it can be used to construct complex heterocyclic systems found in many drug molecules. Researchers looking for a reliable pharmaceutical intermediate manufacturer should consider suppliers offering this compound.
* Agrochemicals: While not explicitly detailed in the source material, pyridine derivatives often find use in agrochemicals. The functional groups allow for modifications that can lead to herbicides, insecticides, or plant growth regulators.
* Materials Science: The molecule can be incorporated into polymers or used in the synthesis of functional materials due to its reactive sites, potentially leading to novel properties in coatings, resins, or advanced composites.
* General Organic Synthesis: Beyond specific industries, 3-Formylpicolinic Acid is a valuable reagent for academic and industrial chemists performing complex organic transformations. Its availability from a trusted chemical supplier like us ensures that your research and development efforts can proceed without interruption.
When seeking to purchase 3-Formylpicolinic Acid, partnering with an experienced manufacturer is key. We provide high-quality 3-Formylpicolinic Acid, ensuring the purity and consistency required for your advanced synthesis projects. Contact us today for a quote and to discuss your bulk purchasing needs.
Perspectives & Insights
Molecule Vision 7
“* Molecular Formula and Weight: With a molecular formula of C7H5NO3 and a molecular weight of 151.”
Alpha Origin 24
“These fundamental properties are essential for stoichiometric calculations in synthesis.”
Future Analyst X
“* Acidity: The presence of a carboxylic acid group (-COOH) lends acidic properties to the molecule, with a predicted pKa of around 4.”