In the vast landscape of organic chemistry, specific intermediates play pivotal roles in enabling the creation of complex molecules. 5-Nitropyridin-3-ylamine, identified by its CAS number 934-59-8, is one such compound, widely recognized for its utility as a synthetic intermediate. This article aims to provide a detailed overview of its chemical properties, synthesis applications, and why it's a sought-after product for chemical manufacturers and researchers looking to buy.

Chemical Identity and Properties
5-Nitropyridin-3-ylamine, also known by synonyms such as 3-Amino-5-nitropyridine or 5-nitro-3-pyridinamine, possesses the molecular formula C5H5N3O2 and a molecular weight of 139.11 g/mol. It typically presents as a light yellow to yellow solid. Key physical properties include:

  • Melting Point: Approximately 162 °C.
  • Boiling Point: Predicted around 367.7 °C at 760 mmHg.
  • Density: Estimated at 1.437 g/cm³.
  • pKa: Approximately 2.13.

These properties are essential for understanding its handling, storage, and reactivity in various chemical processes. The presence of both an amino group and a nitro group on the pyridine ring makes it a versatile molecule for further functionalization.

Synthesis Applications and Significance
The primary application of 5-Nitropyridin-3-ylamine lies in its role as a synthetic intermediate. Its structure allows for participation in a range of organic reactions, making it invaluable for:

  • Building Blocks for Pharmaceuticals: The pyridine scaffold is a common motif in many active pharmaceutical ingredients (APIs). 5-Nitropyridin-3-ylamine can serve as a starting material for synthesizing complex drug molecules, offering routes to novel therapeutic agents. Procurement managers seeking this intermediate for API development can rely on its consistent quality.
  • Agrochemical Development: Similar to pharmaceuticals, the agrochemical industry utilizes sophisticated organic compounds. This intermediate can be a key component in creating new pesticides, herbicides, or plant growth regulators, enhancing crop protection and yield.
  • General Organic Synthesis: Researchers in academic and industrial settings employ 5-Nitropyridin-3-amine in various exploratory syntheses to create novel compounds with potentially useful properties. Its availability from reliable suppliers ensures that such research can proceed without interruption.

Procurement and Sourcing Information
When considering to buy 5-Nitropyridin-3-amine (CAS 934-59-8), it is crucial to partner with reputable manufacturers and suppliers. Companies that specialize in fine chemicals and intermediates, often located in regions like China, provide access to this compound with various purity grades and packaging options (e.g., 25kg/drum). When inquiring, always request the latest pricing, detailed technical specifications, and the Certificate of Analysis (CoA) to ensure product suitability and quality. Understanding the supplier's capacity and commitment to timely delivery is also paramount for efficient research and production workflows.

In essence, 5-Nitropyridin-3-ylamine (CAS 934-59-8) is a foundational compound in many synthetic pathways. Its well-defined chemical properties and broad utility make it an essential item for anyone involved in advanced chemical synthesis. Ensuring a reliable supply chain and stringent quality control from your manufacturer is key to leveraging its full potential.