The Chemical Properties and Synthesis Applications of 7-Bromo-3,4-dihydroquinazolin-4-one
Understanding the chemical properties and reactivity of key organic intermediates is fundamental for any chemist involved in synthesis. 7-Bromo-3,4-dihydroquinazolin-4-one (CAS 194851-16-6) stands out as a valuable compound, owing to its unique structural features and versatile synthetic potential. As a reputable manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality materials that enable researchers and industrial chemists to explore its full utility.
This heterocyclic compound possesses a quinazolinone core substituted with a bromine atom at the 7-position. The bromine atom is a highly functional group, readily participating in various palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. These reactions allow for the introduction of diverse aryl, vinyl, and alkynyl groups, significantly expanding the molecular complexity that can be built from this intermediate. The presence of the amide carbonyl and the nitrogen atoms within the ring also contributes to its chemical reactivity and potential for further derivatization, making it a sought-after building block for drug discovery and materials science.
The typical physical form of 7-Bromo-3,4-dihydroquinazolin-4-one is a white to off-white solid powder, with purity levels often exceeding 98% as determined by HPLC. This high degree of purity is crucial for applications in pharmaceutical synthesis, where even trace impurities can impact the efficacy and safety of the final product. When you are looking to buy this intermediate, ensuring it meets these stringent quality standards from a reliable manufacturer is paramount. We are dedicated to supplying consistent, high-quality 7-Bromo-3,4-dihydroquinazolin-4-one to facilitate your synthesis projects.
The applications of 7-Bromo-3,4-dihydroquinazolin-4-one are wide-ranging, spanning the synthesis of biologically active molecules, functional materials, and agrochemicals. Its utility as a precursor for kinase inhibitors, potential anticancer agents, and other therapeutic compounds is well-documented. For chemists seeking to innovate in these areas, procuring this intermediate from a trusted supplier like us provides a strong starting point. We invite you to explore the potential of this versatile building block and to consider our manufacturing capabilities for your sourcing needs.
Perspectives & Insights
Molecule Vision 7
“The bromine atom is a highly functional group, readily participating in various palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings.”
Alpha Origin 24
“These reactions allow for the introduction of diverse aryl, vinyl, and alkynyl groups, significantly expanding the molecular complexity that can be built from this intermediate.”
Future Analyst X
“The presence of the amide carbonyl and the nitrogen atoms within the ring also contributes to its chemical reactivity and potential for further derivatization, making it a sought-after building block for drug discovery and materials science.”