The Chemical Properties and Synthesis Applications of Boc-D-3-(3-pyridyl)-alanine
Understanding the intrinsic chemical properties of a compound is fundamental to leveraging its full potential in synthesis and research. Boc-D-3-(3-pyridyl)-alanine, a molecule identified by its CAS number 98266-33-2, offers a fascinating combination of features that make it highly sought after in organic synthesis, particularly within the pharmaceutical and peptide chemistry domains.
At its core, Boc-D-3-(3-pyridyl)-alanine is a protected amino acid derivative. The 'Boc' designation refers to the tert-butyloxycarbonyl group, a common acid-labile protecting group used for amines. This group temporarily masks the reactivity of the alpha-amino group, allowing for selective coupling reactions at the carboxyl terminus during peptide bond formation. The 'D' configuration denotes the specific stereochemistry of the alpha-carbon, which is crucial for building peptides with defined three-dimensional structures and biological activities.
The most distinctive feature of this molecule is the '3-(3-pyridyl)' substituent attached to the beta-carbon. This moiety introduces a pyridine ring, a nitrogen-containing heterocycle, into the amino acid side chain. The pyridine ring contributes aromatic character, influences polarity, and provides a site for potential coordination or hydrogen bonding interactions. These characteristics are vital when designing molecules intended to interact with biological targets like enzymes or receptors.
In terms of synthesis applications, Boc-D-3-(3-pyridyl)-alanine is predominantly used in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with altered conformational properties, enhanced stability against enzymatic degradation, and potentially novel pharmacological profiles. Beyond peptide synthesis, it serves as a versatile building block for creating complex heterocyclic compounds and drug candidates in medicinal chemistry. For researchers aiming to buy this compound, ensuring high purity is paramount for reproducible synthetic outcomes.
NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing such advanced chemical intermediates. As a dedicated manufacturer and supplier, we ensure that our Boc-D-3-(3-pyridyl)-alanine meets rigorous purity standards. We serve the global research community, offering reliable sourcing and competitive pricing. If your synthesis projects require this specialized amino acid derivative, we encourage you to contact us for product information and to request a quote. Our commitment is to support your scientific endeavors with high-quality materials.
Perspectives & Insights
Nano Explorer 01
“The 'Boc' designation refers to the tert-butyloxycarbonyl group, a common acid-labile protecting group used for amines.”
Data Catalyst One
“This group temporarily masks the reactivity of the alpha-amino group, allowing for selective coupling reactions at the carboxyl terminus during peptide bond formation.”
Chem Thinker Labs
“The 'D' configuration denotes the specific stereochemistry of the alpha-carbon, which is crucial for building peptides with defined three-dimensional structures and biological activities.”