The Chemical Properties and Synthesis Applications of CAS 70977-72-9
1-(3-Amino-2-hydroxyphenyl)ethanone, identified by CAS number 70977-72-9, is a compound of significant interest in the field of organic chemistry and pharmaceutical development. Its molecular formula, C8H9NO2, and a molecular weight of 151.16 g/mol provide the fundamental structural information. The physical properties, such as a density of 1.242 g/cm³, a boiling point of 287.2 °C at 760 mmHg, and a flash point of 127.5 °C, are crucial for understanding its handling and reaction conditions.
This compound is often described as a pale-yellow to yellow-brown solid, and its chemical structure features an acetophenone core substituted with amino and hydroxyl groups. These functional groups impart specific reactivity, making it a versatile intermediate in various synthesis pathways. The presence of the amino group allows for derivatization through acylation, alkylation, or diazotization, while the hydroxyl group can participate in etherification or esterification reactions.
The primary application of 1-(3-Amino-2-hydroxyphenyl)ethanone lies in its role as a pharmaceutical intermediate. It is a key precursor in the synthesis of ranlukast, a leukotriene receptor antagonist used to manage asthma and allergic rhinitis. The precise chemical synthesis steps involving this intermediate are vital for achieving the desired molecular structure and pharmacological activity of the final API.
Beyond its well-known role in ranlukast synthesis, this compound can also find applications in the development of other fine chemicals, dyes, or specialty materials where its unique combination of functional groups can be leveraged. Researchers continually explore new synthesis pathways and applications for such versatile building blocks. For any chemical product, understanding its specifications and sourcing it from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures the success of your research and production goals.
This compound is often described as a pale-yellow to yellow-brown solid, and its chemical structure features an acetophenone core substituted with amino and hydroxyl groups. These functional groups impart specific reactivity, making it a versatile intermediate in various synthesis pathways. The presence of the amino group allows for derivatization through acylation, alkylation, or diazotization, while the hydroxyl group can participate in etherification or esterification reactions.
The primary application of 1-(3-Amino-2-hydroxyphenyl)ethanone lies in its role as a pharmaceutical intermediate. It is a key precursor in the synthesis of ranlukast, a leukotriene receptor antagonist used to manage asthma and allergic rhinitis. The precise chemical synthesis steps involving this intermediate are vital for achieving the desired molecular structure and pharmacological activity of the final API.
Beyond its well-known role in ranlukast synthesis, this compound can also find applications in the development of other fine chemicals, dyes, or specialty materials where its unique combination of functional groups can be leveraged. Researchers continually explore new synthesis pathways and applications for such versatile building blocks. For any chemical product, understanding its specifications and sourcing it from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures the success of your research and production goals.
Perspectives & Insights
Silicon Analyst 88
“Beyond its well-known role in ranlukast synthesis, this compound can also find applications in the development of other fine chemicals, dyes, or specialty materials where its unique combination of functional groups can be leveraged.”
Quantum Seeker Pro
“Researchers continually explore new synthesis pathways and applications for such versatile building blocks.”
Bio Reader 7
“For any chemical product, understanding its specifications and sourcing it from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.”