Tert-Butyl Glycinate (CAS 6456-74-2) stands out as a pivotal intermediate in the field of organic synthesis, offering a unique combination of chemical properties that make it highly sought after by researchers and manufacturers alike. As a premier chemical supplier, we are dedicated to providing in-depth insights into the materials we offer, helping our clients make informed purchasing decisions. This article explores the key chemical characteristics and synthesis applications of tert-Butyl Glycinate.

Chemically, tert-Butyl Glycinate is an ester of glycine, where the carboxylic acid group is esterified with a tert-butyl alcohol moiety. This structural feature is critical. The tert-butyl group serves as a robust protecting group for the amine functionality, which is common in amino acid chemistry. This protection is advantageous because it can be selectively removed under specific conditions, typically acidic hydrolysis, without affecting other sensitive parts of a molecule. This characteristic is highly valued in complex synthetic routes where precise control over reaction steps is required. When considering purchasing this compound, understanding these properties is key to its effective utilization.

The compound’s molecular formula is C6H13NO2, with a molecular weight of approximately 131.17 g/mol. It typically presents as an oily liquid, which can range in color from clear to pale yellow, depending on its purity. Its solubility profile is also noteworthy; it is generally soluble in common organic solvents like ethanol, methanol, and dichloromethane, but exhibits limited solubility in water, a trait influenced by the hydrophobic tert-butyl group. This solubility in organic media makes it compatible with a wide range of reaction conditions and purification methods.

The primary application of tert-Butyl Glycinate lies in its role as a versatile building block in organic synthesis. It is extensively used in:

  • Peptide Synthesis: As a protected amino acid derivative, it is fundamental in solid-phase and solution-phase peptide synthesis, allowing for the controlled assembly of peptide chains.
  • Pharmaceutical Intermediate: It serves as a crucial starting material or intermediate in the synthesis of various pharmaceuticals, contributing to the creation of complex drug molecules with specific therapeutic actions.
  • Agrochemical Synthesis: The compound is also employed in the production of certain agrochemicals, where its structure can be modified to create effective crop protection agents.
  • Research and Development: In academic and industrial research labs, it is used for exploring new synthetic methodologies and creating novel organic compounds.

For those looking to buy tert-Butyl Glycinate, sourcing from a reputable manufacturer in China ensures access to high-purity material (e.g., 97%min assay). This reliability is crucial for reproducible results in demanding research or manufacturing processes. We, as a dedicated supplier, focus on maintaining these high standards, making it easier for you to procure this essential chemical.

The cost-effectiveness of tert-Butyl Glycinate also makes it an attractive option for large-scale synthesis. By partnering with a competitive supplier, companies can significantly reduce the cost of their raw materials while maintaining the quality of their final products. We encourage inquiries for bulk orders and custom synthesis requirements to explore how we can best support your projects.

In summary, tert-Butyl Glycinate (CAS 6456-74-2) is a valuable and versatile chemical intermediate due to its protective group strategy and its role in constructing complex organic molecules. Its applications in peptide synthesis, pharmaceuticals, and agrochemicals underscore its importance. We are proud to be a leading manufacturer and supplier, offering high-quality tert-Butyl Glycinate to meet your diverse synthetic needs. Contact us today to obtain a quote and secure your supply of this essential building block.