Understanding the intricate details of chemical compounds is vital for any scientist or procurement specialist in the chemical industry. Dibenzofuran-4-boronic acid (CAS: 100124-06-9) is a compound of significant interest due to its unique structure and reactivity. This article explores its key chemical properties and common synthesis routes, offering valuable insights for those looking to buy or utilize this important intermediate.

Dibenzofuran-4-boronic acid is characterized by its dibenzofuran framework, a fused tricyclic aromatic system that confers rigidity and specific electronic properties. Its chemical formula is C12H9BO3, with a molecular weight of approximately 212.01 g/mol. Physically, it typically presents as an off-white powder, and it possesses a notably high melting point, generally ranging from 286 to 291°C. This thermal stability makes it suitable for a variety of reaction conditions, a key consideration for chemists working with it.

The synthesis of Dibenzofuran-4-boronic acid often involves metallation of a suitable dibenzofuran precursor, followed by reaction with a borate ester. A common pathway starts with 4-bromodibenzofuran. This precursor is treated with an organolithium reagent, such as n-butyllithium, at low temperatures (e.g., -78°C) in an anhydrous solvent like tetrahydrofuran (THF). This process generates a lithiated intermediate, which is then reacted with a borate ester, such as trimethyl borate or triisopropyl borate. Subsequent acidic hydrolysis yields the desired Dibenzofuran-4-boronic acid. Manufacturers aim for high yields and purity in these processes.

For procurement purposes, understanding these synthesis pathways can shed light on potential impurities and the importance of quality control. As a dedicated manufacturer, we focus on optimizing these synthetic routes to deliver Dibenzofuran-4-boronic acid with high purity, often exceeding 97%. This commitment ensures that our clients, whether they are purchasing for pharmaceutical research or material science applications, receive a reliable and effective chemical intermediate. When you search for 'how to synthesize Dibenzofuran-4-boronic acid' or 'Dibenzofuran-4-boronic acid synthesis yield', you are looking for information that directly impacts product quality.

The utility of Dibenzofuran-4-boronic acid, particularly its role in Suzuki coupling reactions, makes it an indispensable tool in modern organic chemistry. If your research or production requires this compound, choosing a supplier that prioritizes purity and offers expert support is crucial. We are dedicated to providing high-quality Dibenzofuran-4-boronic acid to meet your needs, ensuring your synthetic projects are successful.