Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate (CAS 1458-01-1) is a molecule of significant interest within the pharmaceutical and fine chemical industries. Its unique heterocyclic structure imparts specific chemical properties that make it a valuable intermediate for complex syntheses. For researchers and procurement professionals, a thorough understanding of its chemistry is fundamental when considering its purchase and application.

The compound's structure is built around a pyrazine ring, a six-membered aromatic heterocycle containing two nitrogen atoms. This core is substituted with two amino groups (-NH2) at positions 3 and 5, a chlorine atom (-Cl) at position 6, and a methyl ester group (-COOCH3) at position 2. This arrangement of functional groups dictates its reactivity. The amino groups confer basic and nucleophilic character, allowing for reactions such as acylation and alkylation. The chlorine atom, being an electron-withdrawing group, activates the pyrazine ring for nucleophilic aromatic substitution under certain conditions. The methyl ester group can undergo hydrolysis to the corresponding carboxylic acid or participate in transesterification reactions.

When chemists look to buy Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate, they are often interested in these reactive sites. The compound's stability is generally good under standard conditions, often stored at 2-8°C. However, it is incompatible with strong oxidizing agents, which can degrade the molecule. Its solubility is moderate in polar organic solvents like DMSO, but limited in water, typical for many organic intermediates.

The synthesis of Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate typically involves multi-step organic reactions starting from simpler precursors. While specific patented routes exist, a common approach might involve the derivatization of pyrazine carboxylic acids or related heterocycles. Manufacturers, especially those in regions like China where specialized chemical synthesis is advanced, invest in optimizing these routes to achieve high yields and purity. For example, a methyl 3,5-diamino-6-chloropyrazine-2-carboxylate manufacturer China will have developed proprietary processes to ensure batch consistency and quality.

Understanding the synthesis pathway is also relevant when considering the CAS 1458-01-1 price. More complex synthesis routes or the need for highly specialized reagents can influence the overall cost. As a pharmaceutical intermediate supplier, providing insight into the synthesis and quality control measures is part of building trust with clients. This knowledge helps researchers and formulators assess the suitability of the compound for their specific projects, whether it's for synthesizing Amiloride or exploring new chemical entities.

In conclusion, the chemical properties and synthesis of Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate are central to its utility. By appreciating its reactivity, stability, and the manufacturing processes behind it, buyers can make more informed decisions when procuring this essential chemical.