Understanding the intrinsic chemical properties and efficient synthesis pathways of key intermediates is fundamental for any B2B player in the chemical and pharmaceutical sectors. (S)-Pyrrolidin-3-ylmethanol, identified by CAS 110013-19-9, is a prime example of such a compound, valued for its versatility in organic synthesis and its application in pharmaceutical research. As a dedicated manufacturer and supplier, we are committed to providing high-quality materials with detailed technical understanding.

(S)-Pyrrolidin-3-ylmethanol, with the molecular formula C5H11NO, is a chiral alcohol featuring a pyrrolidine ring. Its hydrochloride salt form (C5H12ClNO) is often encountered and exhibits properties such as an off-white to pale beige solid appearance. The compound is described as hygroscopic, meaning it readily absorbs moisture from the atmosphere, necessitating proper storage conditions. Its melting point range is typically around 174-176°C for the hydrochloride salt. While slightly soluble in water, it demonstrates better solubility in organic solvents like methanol and DMSO, characteristics that are crucial for reaction optimization.

The synthesis of (S)-Pyrrolidin-3-ylmethanol can be achieved through several established methods. These often involve starting from pyrrolidine and utilizing reactions like formaldehyde addition followed by reduction, or employing chiral pool synthesis and asymmetric synthesis techniques to ensure the correct stereochemistry. The importance of obtaining a single enantiomer is underscored by its role in producing stereospecific drugs, where biological activity is highly dependent on molecular configuration. When considering buying this compound, it’s important to ensure the chosen manufacturer adheres to strict enantioselective synthesis protocols.

Spectroscopic analysis, including NMR and IR, plays a vital role in confirming the structure and purity of (S)-Pyrrolidin-3-ylmethanol. NMR spectroscopy reveals characteristic shifts for the protons and carbons within the pyrrolidine ring and the hydroxymethyl group, providing definitive structural confirmation. Infrared spectroscopy highlights the presence of the hydroxyl and N-H functional groups. For purchasers, these analytical data, typically provided in a Certificate of Analysis (CoA) by a reliable manufacturer, are essential for quality assurance.

In summary, (S)-Pyrrolidin-3-ylmethanol is a compound with well-defined chemical properties and accessible synthesis routes. Its value as a chiral building block in the pharmaceutical industry cannot be overstated. We encourage professionals seeking to purchase this intermediate to contact us for detailed product information, competitive pricing, and reliable supply. Partner with us to secure your source for this critical organic synthesis component.