For chemists and researchers in the field of fine chemicals and pharmaceuticals, a thorough understanding of key intermediates is vital for successful synthesis. 1,2-Dichloro-4-fluorobenzene, identified by its CAS number 1435-49-0, is one such compound. Its unique molecular structure, featuring both chlorine and fluorine substituents on a benzene ring, imparts specific reactivity and utility.

Chemically, 1,2-Dichloro-4-fluorobenzene (C6H3Cl2F) has a molecular weight of approximately 164.99 g/mol. Its physical appearance is consistently described as a clear, colorless to slightly yellow liquid. This physical state makes it relatively easy to handle and measure in laboratory settings. The compound's boiling point is around 172°C, and its density is about 1.403 g/cm³ at 25°C. These properties are critical for process design and optimization when using it as a reactant.

The primary application of 1,2-Dichloro-4-fluorobenzene lies in its role as an intermediate for further chemical synthesis. It is frequently employed in the pharmaceutical industry to construct complex drug molecules. Its halogenated aromatic structure serves as a versatile platform for various reactions, including nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions. Researchers also utilize it in the development of novel agrochemicals and specialty materials.

When purchasing 1,2-Dichloro-4-fluorobenzene, it is essential to procure it from reliable suppliers who guarantee its purity. High purity is crucial for consistent results in sensitive synthesis pathways. Many chemical suppliers in China offer this compound, and it's advisable to compare prices and product specifications to find the best manufacturer for your needs. Engaging with a trusted supplier ensures you receive a quality product for your research and manufacturing endeavors.