For synthetic organic chemists, understanding the inherent reactivity of a chemical intermediate is key to designing efficient and successful reaction pathways. 3-Bromo-2-methylphenol, identified by its CAS number 7766-23-6, is a compound that offers a rich platform for chemical manipulation. At NINGBO INNO PHARMCHEM CO.,LTD., we recognize the importance of this versatility and are a trusted supplier of this crucial building block. This article explores its key reactive sites and synthetic potential.

Functional Groups and Reactivity
3-Bromo-2-methylphenol possesses three primary functional groups that dictate its chemical behavior: the phenolic hydroxyl group, the methyl group, and the bromine atom attached to the aromatic ring. Each of these offers distinct opportunities for synthetic chemists:

  • Phenolic Hydroxyl Group: The hydroxyl group on the aromatic ring exhibits mild acidity and can undergo reactions such as etherification, esterification, and O-alkylation. It can also participate in electrophilic aromatic substitution reactions, often activating the ortho and para positions.
  • Bromine Atom: The bromine atom on the ring can be a site for various transformations. It can be replaced through nucleophilic aromatic substitution under specific conditions, participate in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira coupling), or be used in Grignard reagent formation, further expanding its synthetic utility.
  • Methyl Group: While less reactive than the other functional groups, the methyl group can potentially undergo benzylic bromination or oxidation under specific harsh conditions. Its presence also influences the electronic properties and steric hindrance around the aromatic ring.

The strategic combination of these reactive centers makes 3-Bromo-2-methylphenol an invaluable intermediate for chemists aiming to synthesize complex molecules. For researchers looking to buy this compound, understanding these reactivity patterns is essential for experimental design.

Sourcing High-Quality Intermediates
To fully leverage the synthetic potential of 3-Bromo-2-methylphenol, it is imperative to source it from a reliable manufacturer that guarantees high purity. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing premium intermediates like 3-Bromo-2-methylphenol, ensuring that your reactions proceed smoothly and yield the desired products efficiently. We offer competitive pricing and reliable supply, making us an ideal partner for your synthetic chemistry needs.