For chemists engaged in the synthesis of complex organic molecules, particularly within the pharmaceutical sector, understanding the utility of specific chemical intermediates is key. 2-Chloropyridine-5-acetic acid (CAS: 39891-13-9) stands out as a valuable heterocyclic building block. Its structural features, including the pyridine ring and the acetic acid moiety, confer a unique reactivity profile that is highly sought after in various synthetic pathways. This article delves into the chemical significance of this compound and its applications for researchers and formulators.

Chemical Properties and Structure

2-Chloropyridine-5-acetic acid, with the molecular formula C7H6ClNO2 and a molecular weight of 171.58 g/mol, is characterized by its pyridine core substituted with a chlorine atom and an acetic acid group. The presence of the chlorine atom on the pyridine ring influences its electronic properties, often making it more reactive in nucleophilic substitution reactions compared to its non-chlorinated counterparts. The acetic acid functional group provides a site for further derivatization, such as esterification or amidation, which are common transformations in organic chemistry. Its typical appearance is a white powder, with a melting point range commonly cited between 164-169°C. Sourcing this compound from a reliable manufacturer ensures that these specifications are met, crucial for reproducible synthetic outcomes.

Applications in Organic Synthesis

The versatility of 2-Chloropyridine-5-acetic acid makes it an attractive reagent for various synthetic endeavors. Researchers often seek this compound to build more complex heterocyclic systems, which are prevalent in many pharmaceuticals. Its role as a pharmaceutical intermediate means it can be a precursor to Active Pharmaceutical Ingredients (APIs) or key components within drug discovery pipelines. By leveraging its chemical reactivity, scientists can introduce specific functionalities or structural motifs into target molecules, facilitating the development of new drugs with improved efficacy or pharmacokinetic properties.

For those looking to buy 2-Chloropyridine-5-acetic acid, finding a reputable supplier is essential. A good supplier will not only provide a high-quality product but also offer technical support and relevant documentation. If you are a product formulator or a research scientist, understanding how to effectively utilize this compound can streamline your work. Companies like NINGBO INNO PHARMCHEM CO.,LTD. serve as trusted sources for such critical chemical reagents, ensuring that buyers have access to the materials they need for successful research and development.

Procurement Considerations

When sourcing 2-Chloropyridine-5-acetic acid, it's beneficial to work with suppliers who offer transparent pricing and reliable delivery schedules. As a key component in many synthesis routes, maintaining a consistent stock is important. Exploring options from various chemical suppliers in China can provide a broad overview of availability and pricing. For those seeking to purchase this intermediate, focusing on vendors with a proven track record in quality and customer service will lead to more efficient and successful outcomes.