The precise manipulation of peptide structures is a cornerstone of modern biochemical research and pharmaceutical development. Specialty amino acid derivatives, such as 4-Cyanophenylalanine (H-Phe(4-CN)-OH), offer unique functionalities that enable scientists to tailor peptide properties for specific applications. The introduction of a cyano group onto the phenylalanine side chain provides a distinct electronic and steric profile, making it a valuable tool for altering peptide behavior.

Chemically, H-Phe(4-CN)-OH is an aromatic alpha-amino acid with the molecular formula C10H10N2O2. Its phenyl ring, substituted with a nitrile group at the para position, imparts hydrophobicity and influences the electronic distribution of the side chain. This modification can affect how a peptide interacts with its biological targets, potentially enhancing binding affinity or specificity. For researchers looking to buy this compound, its role in creating peptides with altered physicochemical properties is a major draw.

The synthesis of peptides often involves incorporating such non-canonical amino acids using established solid-phase peptide synthesis (SPPS) or solution-phase methods. H-Phe(4-CN)-OH can be seamlessly integrated into peptide sequences using standard coupling chemistries. Its unique side chain can also influence the overall conformation of the peptide backbone, leading to improved stability against proteolysis or enhanced receptor engagement. Researchers often seek this compound from reliable manufacturers to ensure purity and consistent incorporation efficiency.

The commercial availability of 4-Cyanophenylalanine (CAS 167479-78-9) from trusted suppliers like us is critical for its widespread adoption in research. Whether you are developing novel peptide-based pharmaceuticals, creating diagnostic tools, or exploring fundamental biochemical mechanisms, having access to this specialized amino acid derivative is essential. We encourage scientists to consider the advantages of H-Phe(4-CN)-OH for their projects and to inquire about wholesale and bulk purchase options to optimize their research budgets. Its price point reflects its specialized nature and the intricate synthesis required.