Delving into the molecular architecture and characteristics of pharmaceutical compounds is key to understanding their therapeutic potential and manufacturing requirements. LorcaserinA, a substance identified by CAS 616201-80-0, is a prime example of a molecule designed for a specific pharmacological purpose, notably in the realm of weight management. A thorough examination of its chemical structure and properties provides essential context for its use and study.

LorcaserinA, also known by its chemical name 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, features a benzazepine ring system. This core structure is functionalized with a chlorine atom and a methyl group, contributing to its selective interaction with serotonin receptors. Its molecular formula, C11H14ClN, and a molecular weight of approximately 195.69 g/mol, are fundamental data points for chemists and pharmacologists. The compound typically presents as a white powder, a common physical form for many APIs and their intermediates.

The physical properties of LorcaserinA, such as its boiling point of 288°C and flash point of 128°C, offer insights into its thermal stability and handling considerations. These parameters are critical for safe storage, transportation, and processing during its synthesis and formulation. While its primary application was as an appetite suppressant, its development also involved extensive research into its pharmaceutical applications, particularly its mechanism of action as a selective serotonin 2C receptor agonist.

The journey of LorcaserinA in the pharmaceutical market has been complex. Initially approved for weight management, it was later withdrawn due to concerns about potential cancer risks. This history underscores the rigorous scientific scrutiny and evolving understanding of drug safety. Despite its market withdrawal in some regions, the compound remains a subject of interest for its pharmacological profile and the chemical synthesis methodologies developed for its production. The research surrounding its synthesis, including various intermediate steps and reaction conditions, continues to inform advancements in medicinal chemistry.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying high-quality chemical compounds and intermediates, supporting critical research and development activities. Understanding the detailed chemical and physical properties of substances like LorcaserinA is fundamental to our mission. We strive to provide the necessary materials and information to facilitate the ongoing innovation within the pharmaceutical and chemical industries, enabling advancements in therapeutic solutions.