The field of chemical synthesis is constantly evolving, with researchers seeking versatile and reliable building blocks to create novel molecules. (2-Iodoethyl)benzene, identified by its CAS number 17376-04-4, is a prime example of such a crucial intermediate. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier in China, is dedicated to providing researchers with high-quality (2-Iodoethyl)benzene, essential for a wide array of synthetic applications. This article offers insights into its properties and utility in modern chemistry.

Properties and Reactivity of (2-Iodoethyl)benzene

(2-Iodoethyl)benzene, with the molecular formula C8H9I and a molecular weight of 232.06 g/mol, is typically supplied as a clear, red-brown liquid. Its key physical characteristics include a melting point of -2°C and a boiling point of 122-123°C at 13 mm Hg. The primary driver of its synthetic utility is the carbon-iodine bond, which is relatively weak and polarizable, making the iodine atom an excellent leaving group. This characteristic enables (2-Iodoethyl)benzene to readily participate in nucleophilic substitution reactions (SN1 and SN2), Grignard reactions, and various transition metal-catalyzed coupling reactions (e.g., Heck, Suzuki, Sonogashira couplings).

Key Synthesis Applications

The versatility of (2-Iodoethyl)benzene makes it indispensable in several areas of chemical synthesis:

  • Pharmaceutical Drug Development: It is extensively used in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). The phenethyl moiety is a common structural feature in many therapeutic agents, and (2-Iodoethyl)benzene provides an efficient way to introduce this group or further functionalize it.
  • Organic Synthesis Research: Researchers employ it for C-C bond formation, alkylation of amines, thiols, and alcohols, as well as for creating more complex heterocyclic systems. Its predictable reactivity allows for precise control over reaction outcomes.
  • Agrochemical Synthesis: It can be used as a precursor for certain pesticides and other crop protection chemicals.
  • Materials Science: In some advanced research, it may be incorporated into monomers for specialty polymers or functional materials.

Choosing a Reliable Supplier

For researchers and chemical procurement specialists, selecting a reliable supplier is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity (2-Iodoethyl)benzene (typically 97% min.) sourced directly from our manufacturing facilities in China. This ensures:

  • Quality Consistency: Guaranteed purity for reliable experimental results.
  • Competitive Pricing: Direct sourcing offers significant cost advantages, particularly for laboratory budgets.
  • Dependable Supply: We ensure that this essential intermediate is readily available to support your ongoing research projects.
  • Technical Support: Our team is available to answer questions regarding product specifications and applications.

Conclusion

(2-Iodoethyl)benzene (CAS: 17376-04-4) remains a vital tool in the synthetic chemist's arsenal. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for acquiring this high-quality chemical intermediate. We encourage researchers to inquire about our products and experience the advantages of working with a dedicated Chinese manufacturer and supplier committed to excellence in chemical synthesis.