In the realm of modern chemistry, the ability to manipulate molecular structures and create novel compounds is the bedrock of innovation. Intermediates like 3-Chloro-9H-xanthen-9-one (CAS 27063-50-9) are indispensable tools for chemists, enabling the construction of complex molecules with tailored properties. This article highlights the diverse chemical synthesis applications of this important xanthone derivative and guides you on sourcing it from reliable suppliers.

The Chemical Foundation: 3-Chloro-9H-xanthen-9-one

As a solid compound with the chemical formula C13H7ClO2 and a molecular weight of 230.65 g/mol, 3-Chloro-9H-xanthen-9-one offers a unique platform for chemical reactions. The xanthone core is a fused ring system known for its stability and often associated with interesting photophysical and biological properties. The presence of a chlorine atom adds a crucial point of reactivity, making it a versatile intermediate for further functionalization.

Key Synthesis Pathways and Applications

The versatility of 3-Chloro-9H-xanthen-9-one is evident in its wide range of applications within chemical synthesis:

  • Functional Group Interconversion: The chlorine atom can be replaced through nucleophilic substitution reactions with a variety of functional groups, such as amines, alcohols, thiols, or carbon nucleophiles. This is a foundational method for creating diverse xanthone derivatives.
  • Metal-Catalyzed Cross-Coupling Reactions: This intermediate is an excellent substrate for palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are powerful tools for forming new carbon-carbon bonds, essential for building complex organic architectures. Researchers often seek to buy this compound for these specific transformations.
  • Synthesis of Pharmaceutical Intermediates: Many biologically active compounds feature xanthone structures. 3-Chloro-9H-xanthen-9-one serves as a key starting material or intermediate in the synthetic routes leading to these potential therapeutic agents, contributing to advancements in drug discovery.
  • Development of Advanced Materials: The photophysical properties of xanthone derivatives make them attractive for applications in materials science, such as organic light-emitting diodes (OLEDs), fluorescent dyes, and photostabilizers.

Sourcing High-Quality Intermediates

To effectively utilize 3-Chloro-9H-xanthen-9-one in your synthesis projects, it is critical to source it from a reputable manufacturer or supplier. A reliable provider ensures:

  • High Purity: Guaranteeing a minimum purity of 97% is essential for predictable reaction outcomes.
  • Consistent Quality: Batch-to-batch consistency is vital for reproducible synthesis.
  • Technical Support: Access to technical data and support can aid in optimizing reaction conditions.
  • Competitive Pricing: When you purchase from established chemical producers, particularly manufacturers in China, you can often secure favorable pricing.

Conclusion

3-Chloro-9H-xanthen-9-one is a powerful and versatile tool in the hands of synthetic chemists. Its reactivity and structural features open doors to a wide array of applications, from novel pharmaceuticals to advanced materials. By prioritizing the sourcing of high-purity material from reliable chemical suppliers, researchers and manufacturers can unlock the full potential of this indispensable intermediate and drive innovation in chemical science.