In the intricate world of chemical synthesis, the choice of starting materials significantly impacts the efficiency, yield, and purity of the final product. 2-Fluoro-5-nitrobenzyl bromide, identified by its CAS number 454-15-9, is a compound that has garnered attention for its utility as a versatile intermediate. This article delves into its applications and the critical quality aspects that researchers and product developers must consider when sourcing this chemical.

The Chemical Profile of 2-Fluoro-5-nitrobenzyl Bromide
CAS 454-15-9 is characterized by its molecular formula C7H5BrFNO2 and is typically described as a white powder. Its structure features a fluorinated nitrobenzene ring substituted with a bromomethyl group. This combination of functional groups makes it a reactive species, suitable for various chemical transformations. The benzyl bromide moiety is particularly prone to nucleophilic substitution reactions, allowing for the attachment of diverse molecular fragments. The nitro group can also be modified, often through reduction, to introduce amine functionalities, which are prevalent in many biologically active molecules.

Key Applications in Synthesis
The primary applications of 2-Fluoro-5-nitrobenzyl bromide lie in the fields of agrochemical and pharmaceutical synthesis. It serves as a crucial building block for creating complex organic molecules. For instance, in agrochemistry, it may be used to synthesize novel pesticides or herbicides designed for enhanced efficacy and target specificity. In the pharmaceutical sector, it acts as a precursor for developing new drug candidates, where its specific structural features can contribute to desired pharmacokinetic and pharmacodynamic properties.

Quality Considerations for Synthesis
When undertaking chemical synthesis, the purity of reagents is paramount. For 2-Fluoro-5-nitrobenzyl bromide, a high purity level, typically 99.5% minimum, is often specified to avoid side reactions and ensure a high yield of the desired product. Sourcing from reputable manufacturers, such as NINGBO INNO PHARMCHEM CO.,LTD., is vital. These suppliers provide detailed specifications and Certificates of Analysis (CoA) that confirm the product's quality. Consistency in the supply chain also ensures that research and production timelines are not disrupted. For researchers, obtaining this intermediate can involve purchasing smaller quantities for laboratory use, while industrial clients might require bulk supply in 25kg drums.

Where to Buy and What to Expect
For those looking to buy CAS 454-15-9, engaging with established chemical suppliers who have a strong presence in the market is recommended. These suppliers can offer competitive pricing per kg and provide the necessary technical documentation. Understanding the product's reactivity and application is key to its effective utilization in any synthesis project, ensuring that chemical innovation can proceed smoothly.