In the realm of advanced organic synthesis and pharmaceutical development, specific intermediates play a pivotal role in constructing complex molecular architectures. 2-(1-(Ethylsulfonyl)azetidin-3-ylidene)acetonitrile, identified by CAS number 1187595-85-2, stands out as a critical compound, particularly for its application in the synthesis of Baricitinib, a JAK inhibitor. As a leading chemical supplier, we are dedicated to providing researchers and manufacturers with this high-quality building block.

The chemical profile of 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile is characterized by its unique structure, featuring an ethylsulfonyl group attached to an azetidine ring, further modified with an acetonitrile moiety. Typically presenting as a white powder with a melting point around 67-69°C, this compound offers good solubility in solvents like methanol and chloroform. Its molecular formula is C7H10N2O2S, with a molecular weight of approximately 186.23 g/mol. The purity standards for this intermediate are generally set at a minimum of 98%, a specification that we rigorously maintain to ensure its effectiveness in downstream synthesis.

The primary application driving the demand for this acetonitrile derivative is its role as a key intermediate in the manufacturing of Baricitinib. Baricitinib is a potent Janus kinase (JAK) inhibitor that has shown significant efficacy in treating various inflammatory conditions, most notably rheumatoid arthritis. The precise incorporation of 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile into the Baricitinib synthesis pathway underscores its importance in medicinal chemistry.

For researchers and procurement specialists looking to buy this compound, understanding its utility in organic synthesis is crucial. Beyond its pharmaceutical application, its functional groups make it a versatile reagent for chemists exploring new synthetic routes or developing novel compounds. As a supplier, we emphasize the importance of sourcing from reliable manufacturers who can guarantee consistent quality and availability. Whether for academic research or industrial production, purchasing this high-purity chemical from a reputable source is essential.

Our company, as a prominent chemical manufacturer in China, offers 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile to meet the global demand. We are committed to providing a stable supply chain and competitive pricing, making advanced chemical synthesis more accessible. We encourage you to inquire about our products and explore how our high-quality intermediates can support your innovative chemical projects.