For organic chemists and research scientists, the selection of appropriate starting materials and intermediates is often the linchpin of successful synthesis. 6-Bromo-1,2,4-triazin-3-amine (CAS 69249-22-5) is a valuable chemical building block, offering a unique combination of a triazine ring and a reactive bromine atom, making it a sought-after intermediate in various synthetic routes, notably in the preparation of Benzamide derivatives.

Chemical Profile and Properties

6-Bromo-1,2,4-triazin-3-amine, with the molecular formula C3H3BrN4 and a molecular weight of approximately 174.99 g/mol, presents itself as a powder. Its structural features, including the amine group and the bromine substituent on the triazine ring, provide distinct sites for chemical modification. The boiling point of 373.6°C at 760 mmHg and a density of 1.998 g/cm³ offer insights into its physical behavior during reactions and processing. Proper storage, typically under inert atmosphere and at low temperatures (0°C-6°C), is recommended to maintain its integrity and reactivity, ensuring its efficacy when you buy this compound for your laboratory needs.

Synthetic Utility in Organic Chemistry

The primary utility of 6-Bromo-1,2,4-triazin-3-amine lies in its role as a precursor in organic synthesis. The bromine atom is susceptible to nucleophilic substitution and cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing for the introduction of various carbon-based fragments. The amine group can also be functionalized through acylation, alkylation, or other amine-specific transformations. This dual reactivity makes it an exceptionally useful intermediate for constructing more complex molecular architectures. Chemists looking to synthesize specific Benzamide compounds or explore novel heterocyclic structures will find this intermediate to be a valuable asset in their synthetic toolbox.

Applications Beyond Benzamide Synthesis

While its application as an intermediate in Benzamide synthesis is well-documented, the inherent reactivity of 6-Bromo-1,2,4-triazin-3-amine suggests potential use in other areas of organic chemistry research. It can serve as a scaffold for designing kinase inhibitors, as hinted by some research literature, or as a building block for novel materials science applications. For scientists actively seeking new chemical entities, sourcing this intermediate from reliable manufacturers ensures access to a consistent starting point for exploration. Inquiry about this product for your specific research applications is always welcome.

Sourcing and Procurement Considerations

When procuring 6-Bromo-1,2,4-triazin-3-amine for research and development, it is crucial to partner with reputable chemical suppliers. Factors such as product purity, availability, lead times, and competitive pricing are important considerations. As a manufacturer and supplier, we are committed to providing high-quality 6-Bromo-1,2,4-triazin-3-amine that meets the rigorous standards of organic synthesis. We offer flexible quantities, from research-scale to bulk orders, ensuring that your project's needs are met efficiently and economically. Contact us today to get a quote and discuss your specific requirements for this versatile chemical intermediate.