In the intricate world of organic chemistry, certain molecules stand out due to their versatile utility as building blocks for more complex compounds. 3-Methylphenylacetic Acid (CAS: 621-36-3) is one such compound, prized by researchers and industrial chemists alike for its role in sophisticated synthesis pathways. As a leading chemical manufacturer, we understand the importance of this intermediate and its applications.

Understanding 3-Methylphenylacetic Acid's Structure and Properties:

3-Methylphenylacetic Acid is an aromatic carboxylic acid characterized by a phenyl ring substituted with a methyl group at the meta position, attached to an acetic acid moiety. This structure, with the CAS number 621-36-3, grants it specific chemical properties. Typically appearing as a colorless to off-white powder, it possesses a melting point around 64-66 °C and a boiling point of approximately 231.72 °C. Its solubility in water is moderate, but it dissolves readily in common organic solvents, making it amenable to a wide range of reaction conditions.

Key Applications in Chemical Synthesis:

1. Pharmaceutical Intermediate: The most prominent application of 3-Methylphenylacetic Acid is its function as a reactant in the diastereoselective preparation of arylmethylene-isoindolinones. These isoindolinone derivatives are of significant interest in pharmaceutical research and development, often serving as scaffolds for new drug candidates with potential therapeutic activities. Purchasing high-purity 3-Methylphenylacetic Acid from a reliable supplier is crucial for the success of these sensitive synthetic routes.

2. Organic Building Block: Beyond its pharmaceutical relevance, 3-Methylphenylacetic Acid serves as a fundamental building block in general organic synthesis. Its carboxylic acid functionality allows for esterification, amidation, and other derivatizations, while the aromatic ring and benzylic methylene group offer sites for further chemical modifications. Chemists often use this compound to introduce the m-tolylacetic acid structural motif into larger molecules.

3. Specialty Chemicals Development: The compound's unique structural attributes also make it valuable in the development of other specialty chemicals, including agrochemicals, materials science components, and advanced intermediates. Researchers exploring novel chemical entities frequently turn to such well-defined building blocks.

Sourcing and Availability:

As a dedicated manufacturer of fine chemicals, we ensure a consistent and high-quality supply of 3-Methylphenylacetic Acid. Our production facilities in China are equipped to handle both research-scale and industrial-scale demands. We understand that for chemists and procurement managers, reliability and competitive pricing are key. When you need to buy 3-Methylphenylacetic Acid for your synthesis projects, choosing a reputable supplier like ourselves guarantees product integrity and a smooth procurement process. We encourage you to inquire about our product specifications, pricing for bulk orders, and sample availability.