In the intricate world of organic synthesis, certain molecules serve as indispensable foundational elements, enabling the creation of complex and valuable compounds. 4-Hydroxyquinoline (CAS 611-36-9) stands as one such critical chemical intermediate, widely utilized by researchers and manufacturers in the pharmaceutical and fine chemical sectors. Its unique structural features and reactivity profile make it a sought-after component for a variety of synthetic pathways.

Understanding the Chemical Profile of 4-Hydroxyquinoline

4-Hydroxyquinoline, presenting as a yellow powder, possesses a defined set of physical and chemical properties that dictate its utility. Key parameters include a melting point of 200-202 °C and a boiling point of 264.27 °C, indicating its stability under moderate thermal conditions. Its solubility characteristics, particularly in common organic solvents, further enhance its practicality in laboratory and industrial synthesis. The presence of both a hydroxyl group and the quinoline ring system provides multiple sites for chemical modification, allowing chemists to tailor it for specific target molecules.

Applications as a Synthetic Intermediate

The primary strength of 4-Hydroxyquinoline in chemical synthesis lies in its versatility as a building block. It is instrumental in:

  • Pharmaceutical Synthesis: Its quinoline core is a prevalent feature in many drug molecules, particularly those with antimicrobial or antimalarial activities. Researchers often use it to construct these complex pharmaceutical architectures.
  • Agrochemical Development: Similar to pharmaceuticals, its structural motif can be adapted for creating novel agrochemicals with targeted pest or disease control properties.
  • Materials Science: The compound's inherent properties can be exploited in the synthesis of functional materials, dyes, or specialty polymers.

Beyond these core applications, its function as a scavenger of photogenerated oxygen species also opens avenues for its use in developing photostable compounds or materials.

Sourcing 4-Hydroxyquinoline for Synthesis Projects

For chemists and purchasing managers involved in synthetic chemistry, reliable sourcing of high-quality 4-Hydroxyquinoline is paramount. When selecting a supplier, consider:

  • Purity Levels: High purity is essential to avoid side reactions and ensure the integrity of your synthesized products.
  • Batch-to-Batch Consistency: Reliable manufacturers guarantee that each batch of 4-Hydroxyquinoline meets the same strict specifications.
  • Availability and Lead Times: Ensure the supplier can meet your project's timeline for both small-scale research and larger production orders.
  • Technical Documentation: Access to Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS) is critical for compliance and process safety.

To find a trusted manufacturer or supplier, especially one based in China, utilize search terms like '4-Hydroxyquinoline price,' 'CAS 611-36-9 manufacturer,' or 'buy chemical synthesis intermediate.' Engaging with companies that specialize in fine chemical intermediates will provide access to the quality and support needed for successful synthetic endeavors.

In conclusion, 4-Hydroxyquinoline is a cornerstone in many organic synthesis projects. By understanding its chemical properties and focusing on sourcing from reputable manufacturers, researchers and industry professionals can effectively leverage this versatile compound to drive innovation in chemical development.