The Chemical Versatility of 2-Bromo-5-cyanopyridine in Organic Synthesis
In the intricate world of organic synthesis, certain molecules stand out for their exceptional versatility, offering chemists multiple pathways to construct complex molecular architectures. 2-Bromo-5-cyanopyridine (CAS 139585-70-9) is one such compound, a pyridine derivative celebrated for its dual functionality – the reactive bromine atom and the electron-withdrawing cyano group – which open doors to a wide array of valuable chemical transformations.
From a leading chemical supplier in China, we understand that the utility of 2-Bromo-5-cyanopyridine lies precisely in its synthetic potential. The bromine substituent on the pyridine ring is highly amenable to palladium-catalyzed cross-coupling reactions. Techniques such as the Suzuki-Miyaura coupling, Heck reaction, Sonogashira coupling, and Buchwald-Hartwig amination allow for the facile introduction of aryl, alkenyl, alkynyl, and amino groups, respectively. These reactions are cornerstones in modern synthetic chemistry, enabling the rapid assembly of carbon-carbon and carbon-heteroatom bonds, crucial for drug discovery and material science.
Furthermore, the cyano group (-CN) on the pyridine ring also offers distinct reactivity. It can be hydrolyzed to a carboxylic acid, reduced to an amine, or participate in various addition reactions. The electron-withdrawing nature of the cyano group also influences the reactivity of the pyridine ring itself, potentially activating specific positions for nucleophilic aromatic substitution under appropriate conditions. This dual reactivity profile makes 2-Bromo-5-cyanopyridine a highly sought-after intermediate for researchers aiming to synthesize diverse heterocyclic compounds.
For those looking to buy 2-Bromo-5-cyanopyridine, understanding these chemical properties is key to leveraging its full potential. Whether you are a research scientist or a procurement manager, ensuring the availability of high-purity material (typically ≥98% HPLC) from a reliable manufacturer is essential for successful synthesis outcomes. The price and supply consistency from Chinese chemical suppliers further enhance its attractiveness for both laboratory-scale experiments and industrial-scale production.
The strategic importance of 2-Bromo-5-cyanopyridine in building complex molecules cannot be overstated. Its ability to undergo a multitude of well-established and emerging organic reactions makes it an indispensable tool for chemists pushing the boundaries of molecular design. As a dedicated provider, we ensure that this versatile intermediate is accessible, facilitating innovation across pharmaceutical, agrochemical, and material science fields.
Perspectives & Insights
Molecule Vision 7
“As a dedicated provider, we ensure that this versatile intermediate is accessible, facilitating innovation across pharmaceutical, agrochemical, and material science fields.”
Alpha Origin 24
“In the intricate world of organic synthesis, certain molecules stand out for their exceptional versatility, offering chemists multiple pathways to construct complex molecular architectures.”
Future Analyst X
“2-Bromo-5-cyanopyridine (CAS 139585-70-9) is one such compound, a pyridine derivative celebrated for its dual functionality – the reactive bromine atom and the electron-withdrawing cyano group – which open doors to a wide array of valuable chemical transformations.”