(2-Chloroethyl)benzene, also known by its synonym phenethyl chloride, is a compound that chemists rely on for its versatile reactivity and utility in organic synthesis. With its unique chemical structure, it serves as a crucial intermediate for creating more complex molecules, particularly within the pharmaceutical and fine chemical sectors. Understanding its chemical behavior is key for any R&D scientist or product formulator seeking to innovate and optimize their processes.

Core Reactivity and Functional Groups

At its heart, (2-Chloroethyl)benzene (CAS: 622-24-2) features a phenyl group attached to an ethyl chain, with a chlorine atom at the beta position relative to the phenyl ring. This chlorine atom is a reactive leaving group, making the molecule susceptible to nucleophilic substitution reactions. This characteristic is fundamental to its role as an intermediate. For instance, reaction with a nucleophile can replace the chlorine atom, introducing new functional groups and building more elaborate molecular architectures.

Key Applications in Chemical Synthesis:

  • Pharmaceutical Intermediates: One of the most significant applications of (2-Chloroethyl)benzene is its role as a precursor in the synthesis of pharmaceuticals. Its structure is instrumental in building the carbon backbone for various active pharmaceutical ingredients (APIs). For example, it is a key intermediate in the production of Fingolimod hydrochloride, a vital drug for treating multiple sclerosis. When sourcing for these critical applications, it is imperative to buy high-purity material from reliable manufacturers.
  • Fine Chemical Production: Beyond pharmaceuticals, (2-Chloroethyl)benzene finds use in the broader fine chemical industry. It can be a starting material for synthesizing plasticizers, certain dyes, and other specialty chemicals that require its specific molecular framework for desired properties. Manufacturers often seek this compound for its ability to introduce a phenethyl moiety into target molecules.
  • Building Block for Complex Molecules: In academic and industrial research labs, (2-Chloroethyl)benzene is a valuable tool for creating new organic compounds. Its ability to undergo various substitution and coupling reactions allows for the precise construction of complex molecular structures, facilitating the discovery of new materials and potential drug candidates.

Sourcing High-Quality (2-Chloroethyl)benzene

When you need to buy (2-Chloroethyl)benzene, partnering with a reputable manufacturer like NINGBO INNO PHARMCHEM CO., LTD. ensures you receive a product that meets rigorous quality specifications. As a dedicated supplier and manufacturer in China, we offer (2-Chloroethyl)benzene with high purity (typically ≥98.5% GC) and consistent quality, making it ideal for your demanding synthesis projects. Our aim is to provide researchers and formulators with the essential building blocks they need to drive innovation. Contact us today to inquire about pricing and availability, and discover how our reliable supply can support your R&D and production needs.