Understanding the fundamental chemistry of key organic intermediates is vital for professionals in the chemical and pharmaceutical industries. 1-Methoxy-1-cyclopentene (CAS 1072-59-9) is a compound that warrants attention due to its versatile reactivity and broad applicability. This article explores its chemical properties and highlights its significant roles in various synthesis applications, providing insights for those looking to purchase or utilize this important chemical.

Chemical Properties and Structure

1-Methoxy-1-cyclopentene is an organic compound featuring a five-membered carbon ring with a double bond and a methoxy group attached to one of the olefinic carbons. Its chemical formula is C6H10O, and it has a molecular weight of approximately 98.14 g/mol. Typically appearing as a colorless to yellow liquid, its stability and reactivity are key characteristics that make it a valuable intermediate. The enol ether functionality is particularly significant, enabling participation in a range of electrophilic addition and cycloaddition reactions.

Key Synthesis Applications

The utility of 1-Methoxy-1-cyclopentene spans several critical areas of chemical synthesis:

  • Diels-Alder Reactions: As a conjugated diene or dienophile, depending on the reaction partner, it is instrumental in forming new carbon-carbon bonds and creating cyclic structures. This is fundamental in synthesizing complex organic molecules, including many pharmaceutical precursors.
  • Wittig Reactions: It can be readily converted to suitable precursors for Wittig reactions, allowing for the synthesis of substituted alkenes, which are prevalent in natural products and active pharmaceutical ingredients.
  • Grignard Reagent Applications: Its structure allows it to react with Grignard reagents, further expanding its utility in carbon-carbon bond formation and the introduction of various functional groups.
  • Precursor for Other Intermediates: 1-Methoxy-1-cyclopentene itself can be further modified to yield other valuable chemical intermediates, serving as a foundational building block in multi-step syntheses.

Sourcing for Manufacturing and Research

For chemists and procurement managers looking to buy 1-Methoxy-1-cyclopentene, sourcing from reliable manufacturers is paramount. High purity, typically above 85%, is often required for efficient synthetic applications. When considering purchasing, it's advisable to research suppliers who specialize in fine chemicals and pharmaceutical intermediates. NINGBO INNO PHARMCHEM CO.,LTD., as a direct manufacturer in China, offers this compound with a commitment to quality and consistent supply, making them a valuable partner for businesses and research institutions. Obtaining a quote and reviewing the Certificate of Analysis are essential steps before making a purchase.

Conclusion

The chemical properties of 1-Methoxy-1-cyclopentene (CAS 1072-59-9) position it as a versatile and important intermediate in organic synthesis. Its applications in crucial reactions like Diels-Alder and Wittig highlight its value in pharmaceutical and fine chemical manufacturing. By partnering with reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD., you can ensure access to this critical compound, facilitating your research and production needs.