The Chemistry of 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate)
The compound 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate), identified by CAS number 4330-21-6, is a fascinating molecule that bridges the worlds of carbohydrate chemistry and organic synthesis. Its structure, featuring a deoxyribofuranosyl core protected by p-toluoyl groups and functionalized with a chloride at the anomeric position, endows it with specific reactivity crucial for its applications. This precise chemical architecture makes it a sought-after intermediate for creating more complex organic molecules, especially those with biological relevance.
The synthesis of this compound, often referred to as Hoffer's chlorosugar, is a testament to the sophistication of modern synthetic chemistry. Typical routes involve selective protection and activation steps starting from simpler carbohydrate precursors. The chlorination at the anomeric center is a key transformation, rendering the molecule reactive towards nucleophiles. Detailed synthesis protocols, often found in scientific literature and patents, outline the reagents, conditions, and purification methods required to obtain this intermediate with high fidelity. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. in China are specialists in executing these intricate synthesis pathways, ensuring a consistent supply of this vital component.
The applications of 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate) are primarily centered around its use as a glycosyl donor. It is instrumental in forming glycosidic bonds, a fundamental reaction in carbohydrate chemistry and the synthesis of biologically active molecules. Specifically, it is employed in the preparation of modified nucleosides, which are essential for developing antiviral drugs, anticancer agents, and other therapeutic compounds. The ability to reliably buy such specialized intermediates is crucial for research laboratories and pharmaceutical manufacturing facilities that aim to push the boundaries of medical science. The demand for chemical building blocks that facilitate novel molecular construction is ever-present, and NINGBO INNO PHARMCHEM CO.,LTD. is a key partner in this endeavor, providing high-quality materials essential for groundbreaking research.
The availability of this compound from reputable Chinese suppliers like NINGBO INNO PHARMCHEM CO.,LTD. simplifies the procurement process for global researchers. Its chemical properties, such as its solid form and specific melting point, are indicators of quality. Its role in creating complex structures underscores its importance in drug discovery. As pharmaceutical companies continue to innovate, the need for advanced chemical intermediates will only grow, solidifying the position of suppliers who can consistently deliver high-purity materials.
The synthesis of this compound, often referred to as Hoffer's chlorosugar, is a testament to the sophistication of modern synthetic chemistry. Typical routes involve selective protection and activation steps starting from simpler carbohydrate precursors. The chlorination at the anomeric center is a key transformation, rendering the molecule reactive towards nucleophiles. Detailed synthesis protocols, often found in scientific literature and patents, outline the reagents, conditions, and purification methods required to obtain this intermediate with high fidelity. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. in China are specialists in executing these intricate synthesis pathways, ensuring a consistent supply of this vital component.
The applications of 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate) are primarily centered around its use as a glycosyl donor. It is instrumental in forming glycosidic bonds, a fundamental reaction in carbohydrate chemistry and the synthesis of biologically active molecules. Specifically, it is employed in the preparation of modified nucleosides, which are essential for developing antiviral drugs, anticancer agents, and other therapeutic compounds. The ability to reliably buy such specialized intermediates is crucial for research laboratories and pharmaceutical manufacturing facilities that aim to push the boundaries of medical science. The demand for chemical building blocks that facilitate novel molecular construction is ever-present, and NINGBO INNO PHARMCHEM CO.,LTD. is a key partner in this endeavor, providing high-quality materials essential for groundbreaking research.
The availability of this compound from reputable Chinese suppliers like NINGBO INNO PHARMCHEM CO.,LTD. simplifies the procurement process for global researchers. Its chemical properties, such as its solid form and specific melting point, are indicators of quality. Its role in creating complex structures underscores its importance in drug discovery. As pharmaceutical companies continue to innovate, the need for advanced chemical intermediates will only grow, solidifying the position of suppliers who can consistently deliver high-purity materials.
Perspectives & Insights
Silicon Analyst 88
“The chlorination at the anomeric center is a key transformation, rendering the molecule reactive towards nucleophiles.”
Quantum Seeker Pro
“Detailed synthesis protocols, often found in scientific literature and patents, outline the reagents, conditions, and purification methods required to obtain this intermediate with high fidelity.”
Bio Reader 7
“in China are specialists in executing these intricate synthesis pathways, ensuring a consistent supply of this vital component.”