The Chemistry of 2-Methylbenzeneacetyl Chloride: Applications and Handling
2-Methylbenzeneacetyl Chloride (CAS 10166-09-3) is a valuable reactive chemical intermediate used across various industrial sectors, most notably in the synthesis of pharmaceuticals and agrochemicals. Understanding its chemical nature, applications, and proper handling is crucial for chemists and procurement professionals alike. As a committed manufacturer and supplier, we aim to provide clear insights into this essential compound.
Chemically, 2-Methylbenzeneacetyl Chloride is an acyl chloride derived from 2-methylphenylacetic acid. Its structure features a reactive carbonyl chloride group (-COCl) and an ortho-substituted toluene ring. This combination grants it specific reactivity, making it an efficient acylating agent in organic synthesis. It readily reacts with nucleophiles such as alcohols, amines, and thiols to form esters, amides, and thioesters, respectively. This reactivity is fundamental to its use as a building block in creating more complex molecules. If you are looking to buy 2-Methylbenzeneacetyl Chloride for synthesis, its acylating power is its primary benefit.
The primary applications of 2-Methylbenzeneacetyl Chloride lie in its role as an intermediate. In the pharmaceutical industry, it's employed in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, contributing to treatments for various conditions. Similarly, in the agrochemical sector, it is a key component in manufacturing pesticides and herbicides, aiding in crop protection and yield improvement. Its utility extends to the broader field of fine chemical manufacturing, where it serves as a versatile reagent for creating specialty chemicals with unique properties.
Given its reactive nature, particularly its moisture sensitivity, proper handling and storage of 2-Methylbenzeneacetyl Chloride are paramount. It should be stored in tightly sealed containers in a cool, dry, and well-ventilated area, away from moisture and incompatible materials. When handling, appropriate personal protective equipment (PPE), including gloves, eye protection, and respiratory protection, should be used to prevent skin, eye, and inhalation exposure. As a reliable o-tolylacetyl chloride supplier, we provide comprehensive Safety Data Sheets (SDS) to guide safe usage.
For businesses seeking a dependable source for this compound, considering a direct relationship with a chemical manufacturer like us can offer significant advantages, including competitive CAS 10166-09-3 price points and assurance of quality. We are equipped to meet demands for various quantities, from laboratory research to industrial-scale production. We encourage you to contact us to discuss your requirements and to purchase 2-Methylbenzeneacetyl Chloride for your critical chemical synthesis needs.
Perspectives & Insights
Bio Analyst 88
“This combination grants it specific reactivity, making it an efficient acylating agent in organic synthesis.”
Nano Seeker Pro
“It readily reacts with nucleophiles such as alcohols, amines, and thiols to form esters, amides, and thioesters, respectively.”
Data Reader 7
“This reactivity is fundamental to its use as a building block in creating more complex molecules.”