In the realm of organic chemistry, certain molecules stand out for their versatility and indispensable role in synthesizing more complex compounds. 3-Hydroxy-4-methoxybenzonitrile, identified by its CAS number 52805-46-6, is one such vital chemical. Its unique structure, featuring a nitrile group, a hydroxyl group, and a methoxy group attached to a benzene ring, endows it with a rich reactivity profile, making it a sought-after building block in various chemical industries, particularly pharmaceuticals.

The physical and chemical properties of 3-Hydroxy-4-methoxybenzonitrile are critical for its handling and application. Typically appearing as a white or off-white crystalline powder, it possesses a molecular formula of C8H7NO2 and a molecular weight of 149.15. Its boiling point is approximately 300.8°C at 760 mmHg, with a flash point of 135.7°C, indicating moderate flammability. The density is around 1.24 g/cm³. These characteristics are essential for process engineers and chemists when planning synthesis routes and ensuring safe laboratory practices. For those looking to buy chemicals for research, understanding these properties is the first step.

The synthesis of 3-Hydroxy-4-methoxybenzonitrile primarily involves transforming precursors like isovanillin (3-hydroxy-4-methoxybenzaldehyde). Various established routes exist, often employing reagents like hydroxylamine hydrochloride or sulfate. The purity of the final product is crucial, with manufacturers commonly guaranteeing ≥98% purity for demanding applications. This level of purity is vital for its primary use as a pharmaceutical intermediate, especially in the production of drugs like Gefitinib, where stringent quality control is non-negotiable. When sourcing, buyers often inquire about 'high purity 3-hydroxy-4-methoxybenzonitrile price' to ensure they are obtaining a product suitable for their advanced synthesis needs.

Beyond its prominent role in pharmaceutical synthesis, 3-Hydroxy-4-methoxybenzonitrile serves as an excellent starting material for constructing other specialty chemicals and heterocyclic compounds. Its functional groups can be readily modified through reactions such as alkylation, hydrolysis, or reduction, opening avenues for diverse chemical transformations. Researchers are continually exploring novel synthetic pathways and applications, underscoring the compound's enduring significance. For bulk purchases or inquiries about specific grades, connecting with a reliable chemical supplier or manufacturer is key.

The strategic importance of this benzonitrile derivative cannot be overstated. As a key intermediate, it directly influences the efficiency and success of producing life-saving medications and advanced materials. For any organization seeking to purchase this compound, understanding its properties, typical synthesis methods, and critical applications will help in securing a dependable supply chain. Whether for academic research or industrial manufacturing, identifying a trustworthy manufacturer offering competitive pricing for chemical intermediates is always a priority.