The Chemistry of 3-Pyrrolidinone Hydrochloride: Synthesis and Structure
Understanding the fundamental chemistry of a compound is paramount for any scientist or procurement manager involved in its use. 3-Pyrrolidinone Hydrochloride (CAS 3760-52-9) is a fascinating molecule whose structure dictates its broad utility across various scientific disciplines. As a leading manufacturer and supplier of fine chemical intermediates from China, we are dedicated to providing high-purity compounds along with insights into their chemical nature. If you are looking to buy 3-Pyrrolidinone Hydrochloride, appreciating its chemistry will guide your application and sourcing decisions.
At its core, 3-Pyrrolidinone Hydrochloride is the hydrochloride salt of 3-pyrrolidinone. The 3-pyrrolidinone moiety itself is a cyclic amide, featuring a five-membered ring containing a nitrogen atom and a carbonyl group at the third position relative to the nitrogen. This cyclic structure, often referred to as a lactam, is a foundational element in many biologically active molecules and synthetic pathways. The hydrochloride salt form enhances its stability and often improves its solubility in polar solvents, making it more manageable for laboratory synthesis and formulation. The purity of this compound, typically supplied at ≥97%, is crucial because even minor impurities can interfere with sensitive chemical reactions or biological assays, particularly in pharmaceutical research.
The synthesis of 3-pyrrolidinone and its subsequent conversion to the hydrochloride salt typically involves multi-step organic chemistry processes. While specific proprietary routes vary among manufacturers, common approaches might involve cyclization reactions of suitable precursors containing amino and ester or acid functionalities. For instance, derivatives of amino acids or other bifunctional molecules can be employed to construct the pyrrolidinone ring. The formation of the hydrochloride salt is usually a straightforward acid-base reaction, adding HCl to the free base 3-pyrrolidinone. Our manufacturing expertise in China allows for efficient, large-scale synthesis while maintaining rigorous quality control at each stage, ensuring you receive a product of consistent purity when you buy 3-Pyrrolidinone Hydrochloride from us.
The physical characteristics of 3-Pyrrolidinone Hydrochloride are also important to note. It is generally supplied as a powder, with appearances ranging from light yellow to dark brown, depending on the specific purification and batch. Its melting point, typically between 140-150°C, is an indicator of its solid-state properties and thermal stability. These attributes, combined with its reactivity profile, make it a versatile building block for organic synthesis. For R&D scientists, understanding these chemical and physical properties is key to designing successful experimental protocols. For procurement managers, knowing these details helps in specifying requirements to suppliers.
As a trusted supplier, we are committed to transparency regarding the chemistry of our products. When you decide to buy 3-Pyrrolidinone Hydrochloride, you can rely on our detailed product specifications and analytical data. We ensure that our manufacturing processes in China are optimized for both quality and efficiency, providing you with a superior chemical intermediate. We invite you to contact us for technical discussions or to request a quote for your research and development needs.
Perspectives & Insights
Data Seeker X
“It is generally supplied as a powder, with appearances ranging from light yellow to dark brown, depending on the specific purification and batch.”
Chem Reader AI
“Its melting point, typically between 140-150°C, is an indicator of its solid-state properties and thermal stability.”
Agile Vision 2025
“These attributes, combined with its reactivity profile, make it a versatile building block for organic synthesis.”