Delving into the chemistry of 4-Bromo-2-fluorobiphenyl (CAS 41604-19-7) reveals why this molecule is so valuable in organic synthesis. Its structure, characterized by a biphenyl core substituted with both a bromine and a fluorine atom, imparts unique reactivity and makes it a sought-after intermediate for chemists aiming to create complex molecules. Understanding its properties and synthesis is crucial for anyone looking to buy or work with this compound.

The molecular formula of 4-Bromo-2-fluorobiphenyl is C12H8BrF, with a molecular weight of approximately 251.09 g/mol. Typically, it appears as an off-white to pale yellow crystalline solid, with a melting point in the range of 39-41°C. This physical form makes it relatively easy to handle and measure in laboratory settings. The presence of the electronegative fluorine atom and the versatile bromine atom on the biphenyl system opens up numerous avenues for further chemical transformations.

The synthesis of 4-Bromo-2-fluorobiphenyl often involves multi-step processes starting from simpler aromatic precursors. A common route might begin with compounds like 4-bromo-2-fluoroaniline, which can be diazotized and then subjected to coupling reactions, or involve palladium-catalyzed cross-coupling reactions like Suzuki or Heck couplings if starting from different halogenated or boronated biphenyl precursors. Manufacturers often employ optimized procedures to achieve high yields and purity, such as the 99% purity commonly specified.

For businesses seeking to purchase this intermediate, understanding these synthesis pathways can provide insight into the potential costs and quality variations between different manufacturers. A reliable supplier will be able to provide detailed information about their synthesis methods and quality control procedures. This knowledge is invaluable when comparing a quote from different providers and ensuring you are sourcing a product suitable for your specific application, whether it’s pharmaceutical research or fine chemical production.

In conclusion, the chemical structure and synthesis routes of 4-Bromo-2-fluorobiphenyl are fundamental to its utility. As a key building block, its properties make it indispensable, and understanding its chemistry helps in selecting the right manufacturer and supplier to meet your procurement needs effectively.