The Chemistry of 4-Chloro-4'-hydroxybenzophenone: Applications Beyond Fenofibrate Synthesis
While 4-Chloro-4'-hydroxybenzophenone (CAS 42019-78-3) is widely recognized as a crucial intermediate in the synthesis of fenofibrate, its chemical structure suggests broader applicability in organic chemistry. As a supplier of high-quality intermediates, NINGBO INNO PHARMCHEM CO.,LTD. appreciates the versatility of this compound and its potential in various synthetic routes.
The molecule features a benzophenone core with a chlorine atom on one phenyl ring and a hydroxyl group on the other. This combination of functional groups – a ketone, an aryl halide, and a phenol – makes it a versatile building block for numerous organic transformations. The chlorine atom can participate in nucleophilic aromatic substitution reactions or cross-coupling reactions, such as Suzuki or Heck couplings. The hydroxyl group offers a site for esterification, etherification, or oxidation. The carbonyl group can undergo reduction or Grignard reactions.
These reactive sites open doors for its use in creating a range of complex molecules. Beyond its established role in fenofibrate production, 4-Chloro-4'-hydroxybenzophenone could potentially be utilized in the synthesis of other pharmaceuticals, agrochemicals, or specialty materials. Researchers exploring new reaction methodologies or developing novel compounds might find this intermediate a valuable starting material. Its off-white crystalline powder appearance and high purity (99.0% min assay) make it suitable for precise chemical manipulations.
For chemical manufacturers and research institutions looking to buy 4-Chloro-4'-hydroxybenzophenone, understanding its reactivity profile is key. By partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD., you can ensure access to this versatile intermediate for your diverse synthetic chemistry needs. We are committed to supporting innovation by providing high-quality building blocks essential for groundbreaking chemical research and product development.
Perspectives & Insights
Agile Reader One
“The hydroxyl group offers a site for esterification, etherification, or oxidation.”
Logic Vision Labs
“These reactive sites open doors for its use in creating a range of complex molecules.”
Molecule Origin 88
“Beyond its established role in fenofibrate production, 4-Chloro-4'-hydroxybenzophenone could potentially be utilized in the synthesis of other pharmaceuticals, agrochemicals, or specialty materials.”