The Chemistry of 4-chloropyridin-2-amine: Properties and Synthesis
For chemists and production managers, a thorough understanding of a chemical intermediate's properties is fundamental to its successful application. 4-chloropyridin-2-amine (CAS 19798-80-2) is a compound whose chemical characteristics make it highly valuable in organic synthesis. Familiarizing yourself with these properties can inform your purchasing decisions and optimize its use in your processes.
Physically, 4-chloropyridin-2-amine is presented as an off-white powder, a common form for many organic solids that facilitates handling and weighing in laboratory and industrial settings. Its molecular formula, C5H5ClN2, and molecular weight of 128.56000 indicate a relatively small, yet functionalized molecule. The compound exhibits a notable density of 1.326 g/cm³, and its melting point of 126-127ºC suggests it is a stable solid at room temperature, which is advantageous for storage and transportation. The boiling point of 240.8ºC and a flash point of 99.4ºC provide further insights into its thermal stability and safety parameters, important considerations for manufacturers looking to buy.
Chemically, the presence of both an amino group (-NH2) and a chlorine atom (-Cl) on the pyridine ring imparts significant reactivity to 4-chloropyridin-2-amine. The amino group can participate in nucleophilic reactions or act as a directing group, while the chlorine atom is amenable to various substitution reactions, such as nucleophilic aromatic substitution or cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig). These reactions are cornerstone methodologies in modern organic synthesis, allowing for the construction of diverse and complex molecular architectures.
When you are ready to purchase this intermediate, seeking out a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive a product with the specified purity and consistent chemical behavior. Understanding these chemical properties helps R&D scientists and product formulators better integrate 4-chloropyridin-2-amine into their synthesis schemes.
Perspectives & Insights
Nano Explorer 01
“Familiarizing yourself with these properties can inform your purchasing decisions and optimize its use in your processes.”
Data Catalyst One
“Physically, 4-chloropyridin-2-amine is presented as an off-white powder, a common form for many organic solids that facilitates handling and weighing in laboratory and industrial settings.”
Chem Thinker Labs
“326 g/cm³, and its melting point of 126-127ºC suggests it is a stable solid at room temperature, which is advantageous for storage and transportation.”