Understanding the Chemistry: 4-(Difluoromethoxy)aniline as a Versatile Organic Building Block
In the intricate world of organic synthesis, the availability of versatile and high-quality building blocks is paramount for innovation. 4-(difluoromethoxy)aniline, identified by its CAS number 22236-10-8, has emerged as a crucial intermediate, prized for its unique chemical structure and broad applicability. As a leading manufacturer of this compound, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing researchers and industrial chemists with a reliable source of this essential material. Understanding its properties and potential is key to unlocking new synthetic pathways.
The molecular structure of 4-(difluoromethoxy)aniline (C7H7F2NO) features an aniline group substituted at the para position with a difluoromethoxy functional group. This combination imbues the molecule with distinct reactivity and electronic characteristics. The aromatic amine functionality allows for facile participation in a multitude of reactions, including amidation, alkylation, and diazotization, common in the synthesis of pharmaceuticals and advanced materials. Concurrently, the electron-withdrawing nature of the difluoromethoxy group influences the reactivity of the aromatic ring and the nitrogen atom, offering a nuanced control over reaction outcomes. For chemists looking to buy this intermediate, its dual functionality presents significant synthetic advantages.
The utility of 4-(difluoromethoxy)aniline as a building block is perhaps most evident in its role in creating fluorinated organic compounds. The incorporation of fluorine is a well-established strategy for modulating properties such as lipophilicity, metabolic stability, and binding affinity, making it invaluable in medicinal chemistry and agrochemical development. Researchers can reliably purchase this intermediate from our established supply chain in China to construct novel molecules with potentially enhanced biological activities or material properties. We ensure rigorous quality control, offering an assay of ≥98.0% to guarantee performance.
Beyond its applications in pharmaceutical and agrochemical research, 4-(difluoromethoxy)aniline is a valuable tool for academic and industrial researchers exploring novel organic materials, dyes, and specialty chemicals. Its availability at a competitive price from a trusted supplier like us makes it an accessible option for scaling up research projects or for routine synthesis. To inquire about bulk quantities or to obtain a detailed quote, we encourage you to contact our sales representatives. Discover the synthetic potential of this versatile organic intermediate by partnering with a reliable manufacturer.
Perspectives & Insights
Core Pioneer 24
“The aromatic amine functionality allows for facile participation in a multitude of reactions, including amidation, alkylation, and diazotization, common in the synthesis of pharmaceuticals and advanced materials.”
Silicon Explorer X
“Concurrently, the electron-withdrawing nature of the difluoromethoxy group influences the reactivity of the aromatic ring and the nitrogen atom, offering a nuanced control over reaction outcomes.”
Quantum Catalyst AI
“For chemists looking to buy this intermediate, its dual functionality presents significant synthetic advantages.”