For researchers and chemists engaged in organic synthesis, a deep understanding of chemical intermediates is vital. 6-Bromo-1,2,3,4-tetrahydroquinoline, identified by CAS number 22190-35-8, is a heterocyclic compound of significant interest due to its versatile structure and reactivity. This article explores its key chemical properties and common synthesis pathways, providing valuable insights for those looking to procure this essential building block from reliable sources.

The molecular structure of 6-Bromo-1,2,3,4-tetrahydroquinoline combines a saturated nitrogen-containing ring fused with a brominated benzene ring. Its molecular formula is C9H10BrN, with a molecular weight of 212.09 g/mol. Typically presented as a white solid, it requires storage at low temperatures (2-8°C) to maintain its integrity and purity. These physical and chemical characteristics make it a practical intermediate for laboratory-scale reactions and industrial production alike. When you need to buy this compound, confirming these details with your supplier is a good practice.

The synthesis of 6-Bromo-1,2,3,4-tetrahydroquinoline often involves the bromination of 1,2,3,4-tetrahydroquinoline. Common reagents used for this transformation include N-bromosuccinimide (NBS) in a suitable solvent like acetonitrile. The reaction conditions, such as temperature and reaction time, are optimized to achieve good yields and purity. Post-treatment typically involves extraction and purification steps, often using column chromatography. For professionals seeking to purchase this intermediate, understanding its synthetic origin can provide confidence in its quality.

The utility of 6-Bromo-1,2,3,4-tetrahydroquinoline lies in its potential for further chemical modifications. The bromine atom serves as an excellent handle for various coupling reactions, such as palladium-catalyzed cross-couplings. This allows for the introduction of diverse functional groups and the construction of more complex molecular frameworks, which are crucial in drug discovery and materials science. For those looking to buy, inquire about the typical purity levels and analytical data provided by the manufacturer.

As a premier supplier and manufacturer from China, we are dedicated to providing high-quality 6-Bromo-1,2,3,4-tetrahydroquinoline. We understand the importance of reliable intermediates for your research and development projects. When you need to purchase this compound, our team is ready to assist with product inquiries, pricing, and technical support, ensuring you receive material that meets your stringent synthesis requirements.