Understanding the fundamental chemical properties of key intermediates is crucial for successful synthesis and application. 6-Fluoronicotinic Acid, identified by CAS number 403-45-2, is a compound of significant interest in the pharmaceutical and fine chemical industries. This article delves into its core properties and provides insights into synthesis and handling considerations, aimed at R&D scientists and procurement managers.

Chemically, 6-Fluoronicotinic Acid (C6H4FNO2) is a derivative of nicotinic acid, a form of Vitamin B3. The presence of a fluorine atom at the 6-position of the pyridine ring significantly influences its electronic properties and reactivity compared to unsubstituted nicotinic acid. Key physical characteristics include an appearance of off-white crystal powder, a melting point typically ranging from 144-148°C, and a molecular weight of 141.10 g/mol. These properties are vital for anyone looking to buy this compound for specific reactions or formulations.

The synthesis of 6-Fluoronicotinic Acid often involves complex organic chemical routes. While specific proprietary methods vary among manufacturers, typical approaches might involve the functionalization of pyridine precursors or the modification of existing nicotinic acid structures. For end-users, the focus is less on the intricate synthesis pathways and more on ensuring the purity and consistency of the final product. Sourcing from reputable manufacturers who specialize in fluorinated intermediates is therefore paramount.

Handling 6-Fluoronicotinic Acid requires adherence to standard laboratory safety protocols. As with many fine chemicals, it is classified as an irritant, with potential for skin, eye, and respiratory tract irritation. Proper personal protective equipment (PPE), including gloves, safety glasses, and appropriate respiratory protection in dusty environments, is essential. Storage in a cool, dry, and well-ventilated area, away from incompatible materials like strong oxidizing agents, is recommended to maintain its stability and integrity. Purchasing from suppliers who provide comprehensive Safety Data Sheets (SDS) is a standard practice for ensuring safe handling.

As a leading manufacturer and supplier of specialty chemicals, we offer high-purity 6-Fluoronicotinic Acid (CAS 403-45-2). Our commitment is to provide researchers and manufacturers with reliable access to this important intermediate, supported by competitive pricing and efficient logistics. For those seeking to buy 6-Fluoronicotinic Acid, our company stands as a trusted partner in China, ensuring quality and consistent availability for your critical R&D and production needs.

Contact us to obtain a quote and sample of 6-Fluoronicotinic Acid and experience the difference quality sourcing makes.