The Chemistry of Acotiamide Trihydrate: Mechanism and Synthesis
Acotiamide Trihydrate, identified by CAS number 773092-05-0, is a complex organic molecule with significant applications in the pharmaceutical sector. Its chemical structure and properties underpin its function as a gastrointestinal prokinetic agent, making it an invaluable intermediate for drug synthesis. Understanding its chemistry is key to appreciating its therapeutic role and the manufacturing intricacies involved.
The molecular formula C21H31ClN4O5S and a molecular weight of approximately 487.01 g/mol characterize Acotiamide Trihydrate. Its mechanism of action is sophisticated, primarily targeting the gastrointestinal tract by enhancing acetylcholine release from enteric neurons. This is achieved through the selective antagonism of muscarinic acetylcholine receptors M1 and M2, coupled with the inhibition of acetylcholinesterase (AChE). This dual action results in improved gastric emptying and accommodation, which are crucial for managing conditions like functional dyspepsia.
The synthesis of Acotiamide Trihydrate is a multi-step process that demands expertise in organic chemistry. Typically, it involves the conversion of a precursor acid to an acid chloride, followed by coupling with a thiazole amine. Subsequent steps include amide linkage formation, selective demethylation, and salt formation, culminating in the hydrochloride trihydrate form. Each stage requires precise control of reaction conditions and purification techniques to ensure high purity.
NINGBO INNO PHARMCHEM CO.,LTD., as a professional manufacturer and supplier, is adept at navigating these complex synthesis routes. We leverage our chemical expertise to produce Acotiamide Trihydrate that meets the highest industry standards. Our dedication to advanced chemical synthesis ensures a consistent supply of this vital intermediate for pharmaceutical research and production. We encourage interested parties to learn more about our manufacturing capabilities and the competitive price for purchasing this compound.
In conclusion, the chemistry of Acotiamide Trihydrate, from its molecular structure to its detailed synthesis, highlights its importance as a pharmaceutical intermediate. Its targeted mechanism of action makes it a critical component in treatments for digestive disorders, underscoring the need for reliable, high-quality suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
The molecular formula C21H31ClN4O5S and a molecular weight of approximately 487.01 g/mol characterize Acotiamide Trihydrate. Its mechanism of action is sophisticated, primarily targeting the gastrointestinal tract by enhancing acetylcholine release from enteric neurons. This is achieved through the selective antagonism of muscarinic acetylcholine receptors M1 and M2, coupled with the inhibition of acetylcholinesterase (AChE). This dual action results in improved gastric emptying and accommodation, which are crucial for managing conditions like functional dyspepsia.
The synthesis of Acotiamide Trihydrate is a multi-step process that demands expertise in organic chemistry. Typically, it involves the conversion of a precursor acid to an acid chloride, followed by coupling with a thiazole amine. Subsequent steps include amide linkage formation, selective demethylation, and salt formation, culminating in the hydrochloride trihydrate form. Each stage requires precise control of reaction conditions and purification techniques to ensure high purity.
NINGBO INNO PHARMCHEM CO.,LTD., as a professional manufacturer and supplier, is adept at navigating these complex synthesis routes. We leverage our chemical expertise to produce Acotiamide Trihydrate that meets the highest industry standards. Our dedication to advanced chemical synthesis ensures a consistent supply of this vital intermediate for pharmaceutical research and production. We encourage interested parties to learn more about our manufacturing capabilities and the competitive price for purchasing this compound.
In conclusion, the chemistry of Acotiamide Trihydrate, from its molecular structure to its detailed synthesis, highlights its importance as a pharmaceutical intermediate. Its targeted mechanism of action makes it a critical component in treatments for digestive disorders, underscoring the need for reliable, high-quality suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
Perspectives & Insights
Chem Catalyst Pro
“Subsequent steps include amide linkage formation, selective demethylation, and salt formation, culminating in the hydrochloride trihydrate form.”
Agile Thinker 7
“Each stage requires precise control of reaction conditions and purification techniques to ensure high purity.”
Logic Spark 24
“, as a professional manufacturer and supplier, is adept at navigating these complex synthesis routes.”