Antipyrine, also known as Phenazone (CAS 60-80-0), is a fascinating chemical compound belonging to the pyrazolone class. Its unique chemical structure and properties have historically positioned it as a significant medicinal agent and currently as a valuable pharmaceutical intermediate and research chemical. For chemists, formulators, and R&D professionals, understanding the chemistry of Antipyrine is key to its effective application. This article delves into its properties, synthesis pathways, and pharmaceutical significance, offering insights for those looking to buy Antipyrine from manufacturers.

The chemical structure of Antipyrine is characterized by a pyrazole ring system. Specifically, it is a derivative of 1,2-dihydropyrazol-3-one, substituted with methyl groups at the N-1 and C-5 positions and a phenyl group at the N-2 position. This structure (C11H12N2O) contributes to its analgesic, antipyretic, and anti-inflammatory activities. As a white crystalline powder, it exhibits good solubility in water and organic solvents like ethanol and chloroform, facilitating its use in various chemical reactions and formulations. Its stability under standard storage conditions makes it a reliable compound for long-term use. Researchers often seek high purity Antipyrine, typically above 98%, to ensure the accuracy of their analytical and synthetic work.

The synthesis of Antipyrine has been a subject of chemical research since its discovery. Early methods involved reactions of phenylhydrazines with beta-keto esters, followed by methylation. For instance, a common route involves the condensation of 1-phenyl-3-methyl-5-pyrazolone with methyl iodide or dimethyl sulfate. Manufacturers utilize optimized processes to yield Antipyrine efficiently and at high purity. Understanding these synthesis pathways can be beneficial for those interested in the chemical processes behind this vital intermediate and highlights the importance of sourcing from manufacturers with expertise in chemical synthesis.

The pharmaceutical relevance of Antipyrine extends beyond its historical use. It serves as a critical intermediate in the synthesis of various other pharmaceutical compounds. Its functional groups allow for further chemical modifications, making it a versatile building block in medicinal chemistry. For companies looking to purchase Antipyrine, engaging with a specialized Antipyrine manufacturer ensures access to a consistently high-quality raw material. The Antipyrine powder price can vary, but sourcing directly from a primary manufacturer often provides the best value, especially for bulk requirements.

In conclusion, Antipyrine's chemical composition and synthetic accessibility underscore its importance in the chemical and pharmaceutical industries. By understanding its chemistry and sourcing it from reputable suppliers, researchers and manufacturers can leverage this key pyrazolone derivative for a wide range of applications, from advanced drug synthesis to critical analytical studies.