At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on understanding the intricate chemistry that drives pharmaceutical innovation. 2'-Deoxy-2'-fluoroguanosine (CAS 78842-13-4) is a compound whose synthesis and properties are of significant interest, particularly for its role in antiviral research and as a pharmaceutical intermediate.

The synthesis of 2'-deoxy-2'-fluoroguanosine involves complex organic chemistry, often starting from guanosine or related precursors. Key steps typically include selective protection of functional groups, introduction of the fluorine atom at the 2' position of the deoxyribose ring, and subsequent deprotection. These multi-step processes require precise control over reaction conditions to achieve high yields and purity, ensuring the compound's suitability for critical applications.

Chemically, 2'-deoxy-2'-fluoroguanosine is classified as a modified nucleoside analog. Its molecular formula is C10H12FN5O4, with a molecular weight of approximately 285.23 g/mol. The presence of the fluorine atom is critical, as it influences the electronic properties and metabolic stability of the molecule. This modification enhances its resistance to enzymatic degradation, a common hurdle for many antiviral agents.

The properties of 2'-deoxy-2'-fluoroguanosine also include its potent activity as an inhibitor of viral enzymes, particularly viral polymerases involved in RNA synthesis. This makes it a valuable tool for studying viral replication and a promising candidate for the development of new antiviral drugs, especially against influenza viruses. Its physical form is typically a white to off-white powder.

For researchers and developers looking to purchase 2'-deoxy-2'-fluoroguanosine, understanding its chemical profile and synthesis is crucial. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality 2'-deoxy-2'-fluoroguanosine, ensuring that its chemical integrity is maintained, supporting crucial research and development efforts in the pharmaceutical and biochemical industries.