For scientists and product formulators, understanding the chemical nuances of key intermediates is vital for successful research and development. 2-Amino-4-bromophenol (CAS 40925-68-6) is a compound that offers significant versatility in organic synthesis due to its unique structural features. This article explores its chemical properties, common synthesis routes, and diverse applications, highlighting its importance as a valuable raw material. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading manufacturer and supplier of this critical intermediate, offering it at competitive prices to researchers and manufacturers worldwide.

Chemical Properties and Reactivity

2-Amino-4-bromophenol is characterized by its aromatic ring substituted with an amino group (-NH2), a hydroxyl group (-OH), and a bromine atom (-Br). This trifunctional arrangement makes it a highly reactive molecule, capable of participating in a multitude of chemical reactions:

  • Nucleophilic Substitution: The hydroxyl and amino groups can undergo various reactions, such as acylation, alkylation, and esterification.
  • Electrophilic Aromatic Substitution: The bromine atom can be displaced or further functionalized under specific reaction conditions.
  • Coupling Reactions: It is frequently employed in palladium-catalyzed cross-coupling reactions, like the Suzuki-Miyaura coupling, to form new carbon-carbon bonds. This makes it a popular choice for those searching for 'buy 2-amino-4-bromophenol for coupling reactions'.
  • Oxidative Amination: The compound is also utilized in copper-catalyzed oxidative amination processes, essential for synthesizing nitrogen-containing heterocycles.

With a purity of ≥98.0% (GC), our 2-Amino-4-bromophenol ensures predictable and reliable reactivity for your synthesis needs.

Synthesis Methods: A Glimpse into Production

The preparation of 2-Amino-4-bromophenol typically involves the reduction of 4-bromo-2-nitrophenol. This process requires careful control of reaction conditions, including the choice of reducing agent and solvent, to achieve high yields and purity. Understanding the synthesis process is key for anyone inquiring about '2-amino-4-bromophenol manufacturer'. At NINGBO INNO PHARMCHEM CO.,LTD., we employ optimized synthesis and purification protocols to deliver a product that meets the highest industry standards.

Diverse Applications in Research and Industry

The versatility of 2-Amino-4-bromophenol translates into a broad spectrum of applications:

  • Pharmaceutical Intermediates: It is a cornerstone for synthesizing molecules with potential pharmaceutical activity, including kinase inhibitors and other therapeutic agents. Researchers often seek 'high purity 2-amino-4-bromophenol intermediate' for their drug discovery programs.
  • Agrochemicals: It can be incorporated into the synthesis of pesticides and herbicides, contributing to crop protection.
  • Specialty Chemicals: Its unique structure makes it valuable for creating dyes, functional materials, and other specialty chemicals.

For those needing this vital compound, inquiring about '2-amino-4-bromophenol price' from a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD. is the next logical step. We are committed to being your preferred source for this essential organic reagent.