Understanding the fundamental chemistry of key intermediates is vital for their effective utilization. NINGBO INNO PHARMCHEM CO.,LTD. offers insights into 2-Methyl-4-(trifluoromethoxy)aniline (CAS 86256-59-9), detailing its molecular structure, inherent properties, and common synthesis routes. This compound, an aromatic amine, features a benzene ring substituted with a methyl group at the ortho position and a trifluoromethoxy group (-OCF₃) at the para position relative to the amine. Its molecular formula is C₈H₈F₃NO, and it possesses a molecular weight of approximately 191.15 g/mol.

The trifluoromethoxy group is particularly noteworthy. It is a strong electron-withdrawing substituent due to the highly electronegative fluorine atoms. This feature significantly impacts the electron density of the aromatic ring and the basicity of the amino group, influencing the compound's reactivity in various chemical transformations. For instance, it can activate or deactivate certain positions on the ring towards electrophilic or nucleophilic substitution reactions, making it a versatile building block in organic synthesis. The compound typically appears as a solid, with specific melting and boiling points detailed in technical specifications for purchasers.

While specific proprietary synthesis methods vary, the preparation of 2-Methyl-4-(trifluoromethoxy)aniline generally involves introducing the methyl and trifluoromethoxy functionalities onto an aniline or toluene precursor. Common strategies might include regioselective halogenation followed by nucleophilic substitution with fluoride sources to create the trifluoromethoxy group, or methylation reactions on appropriately substituted precursors. The purification process is critical to ensure high purity, often exceeding 97%, which is essential for its use as a pharmaceutical intermediate or in sensitive agrochemical applications. Sourcing this compound with guaranteed purity for purchase is a key consideration.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive technical information to our clients, ensuring they can fully leverage the capabilities of intermediates like 2-Methyl-4-(trifluoromethoxy)aniline. Our dedication to quality control guarantees that the product meets the rigorous standards required by industries ranging from pharmaceuticals to advanced materials. By understanding the chemistry behind this compound, researchers and manufacturers can unlock its full potential in their innovative projects.

In essence, the molecular architecture of 2-Methyl-4-(trifluoromethoxy)aniline makes it a powerful tool for chemists. Its predictable reactivity and the beneficial properties imparted by the trifluoromethoxy group position it as a valuable intermediate for synthesizing complex molecules that address critical needs in health, agriculture, and technology.