The Chemistry Behind 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid: Properties and Synthesis
For professionals engaged in chemical research and development, a deep understanding of intermediate compounds is key to innovation. 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid (CAS: 53197-57-2) is a significant molecule within the realm of organic chemistry, valued for its bifunctional nature and its utility in constructing more complex molecular architectures. This article explores the fundamental chemical properties and common synthesis routes for this vital compound, providing insights for researchers looking to buy high-quality material.
At its core, 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid is a derivative of biphenyl, a structure consisting of two phenyl rings directly linked by a single bond. The presence of two hydroxyl (-OH) groups and one carboxylic acid (-COOH) group at specific positions (4,4'-dihydroxy and 2-carboxylic acid) makes it a highly reactive and versatile building block. These functional groups allow for a variety of chemical transformations, including esterification, etherification, and amide bond formation. Its molecular formula is C13H10O4, with a molecular weight of 230.21600. Typically presented as a white powder, its solid state and defined melting point (around 269.5-270 °C) are important for practical handling and characterization in synthesis.
The synthesis of 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid often involves multi-step organic reactions. While specific proprietary methods may vary among manufacturers, common strategies might include electrophilic aromatic substitution reactions, coupling reactions, or functional group transformations on pre-existing biphenyl structures. For instance, a route could involve the selective hydroxylation and carboxylation of biphenyl precursors. The precise control over reaction conditions, catalysts, and purification techniques employed by a reputable supplier is critical to achieving the high purity (often 97%+) required for demanding applications, particularly in pharmaceutical synthesis. Researchers often rely on detailed analytical data, such as NMR and Mass Spectrometry, to confirm the structure and purity of the procured material.
The value proposition of 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid lies in its role as a precursor. In pharmaceutical R&D, it might be used to synthesize molecules that target specific biological pathways, or as a scaffold for developing new anti-inflammatory agents or other therapeutic compounds. Its rigid biphenyl core, combined with the adaptable hydroxyl and carboxylic acid functionalities, makes it an attractive starting material for drug discovery programs. For scientists aiming to synthesize novel compounds, ensuring a reliable source for this intermediate is paramount. Engaging with a trusted chemical manufacturer in China can provide access to the necessary quantities and consistent quality.
When considering the purchase of 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid, understanding its chemical reactivity is beneficial. The phenolic hydroxyl groups can be easily derivatized, and the carboxylic acid can be converted into esters, amides, or acid halides, opening up numerous synthetic possibilities. Exploring the offered price points from various suppliers will help in budgeting for research projects. Always inquire about the availability of technical data sheets and safety information to ensure proper handling and experimental design.
In essence, 4,4'-Dihydroxy-biphenyl-2-carboxylic Acid is more than just a chemical; it's a key enabler of molecular innovation. Its well-defined chemical properties and versatile reactivity make it indispensable for advanced synthesis. By seeking out reliable manufacturers and suppliers, R&D professionals can ensure they have access to the high-quality intermediates needed to push the boundaries of scientific discovery.
Perspectives & Insights
Alpha Spark Labs
“The presence of two hydroxyl (-OH) groups and one carboxylic acid (-COOH) group at specific positions (4,4'-dihydroxy and 2-carboxylic acid) makes it a highly reactive and versatile building block.”
Future Pioneer 88
“These functional groups allow for a variety of chemical transformations, including esterification, etherification, and amide bond formation.”
Core Explorer Pro
“Typically presented as a white powder, its solid state and defined melting point (around 269.”