The world of organic chemistry is built upon a foundation of versatile building blocks, and 4-Bromo-2-thiophenecarboxylic Acid (CAS: 16694-18-1) is a prime example. This heterocyclic compound, featuring a thiophene ring substituted with both a bromine atom and a carboxylic acid group, offers a rich platform for chemical transformations. Its utility as a pharmaceutical intermediate and a reagent in advanced organic synthesis makes it a compound of significant interest to researchers and manufacturers alike.

Understanding the chemistry of 4-Bromo-2-thiophenecarboxylic acid begins with its structure. The thiophene ring, an aromatic heterocycle containing sulfur, provides unique electronic properties. The bromine atom, strategically placed at the 4-position, is an excellent leaving group, making it highly amenable to various coupling reactions, such as palladium-catalyzed cross-couplings. This reactivity is central to its role in building more complex molecular structures. The carboxylic acid group at the 2-position offers another handle for functionalization, readily participating in esterification, amidation, and decarboxylation reactions. These combined features make it an invaluable tool for synthetic chemists.

As a manufacturer and supplier, we often receive inquiries about the synthesis of 4-Bromo-2-thiophenecarboxylic acid. While specific proprietary methods vary, common approaches involve the functionalization of thiophene derivatives. The precise placement of the bromine and carboxylic acid groups is critical for its downstream applications. Ensuring high purity, typically 97% or greater, is essential for predictable reaction outcomes, especially in the pharmaceutical industry where impurity profiles are strictly regulated. Potential buyers should always verify the product's appearance (white to slightly pale yellow powder or crystals) and specifications when they buy.

The applications of 4-Bromo-2-thiophenecarboxylic acid are diverse. It serves as a key intermediate in the synthesis of various pharmaceutical compounds, including potential anti-cancer agents, antivirals, and central nervous system (CNS) drugs. Beyond pharmaceuticals, its derivatives find use in materials science, particularly in the development of organic electronic materials due to the thiophene core's conductive properties. Researchers looking to buy this compound for specific applications can rely on our services as a dedicated supplier in China.

For those seeking to integrate 4-Bromo-2-thiophenecarboxylic acid into their research or production, understanding its chemical behavior is as important as securing a reliable supply. We are committed to providing high-quality materials that meet rigorous industry standards. If you are a scientist or a procurement manager needing this essential thiophene building block, consider our capabilities as a leading manufacturer. We offer competitive pricing and a commitment to customer satisfaction. Contact us to learn more about our product and to request a quotation or sample.