In the intricate world of organic synthesis, understanding the core chemistry of key intermediates is fundamental. 4-(Difluoromethyl)benzonitrile (CAS: 55805-10-2) stands out as a valuable compound, often employed in creating more complex molecules. For R&D professionals and product formulators, a deeper dive into its characteristics, synthesis, and reliable sourcing is essential.

Chemical Identity and Properties

4-(Difluoromethyl)benzonitrile is characterized by its molecular formula C8H5F2NO and a molecular weight of 153.13 g/mol. Its structure features a benzonitrile core with a difluoromethyl group (-CHF2) at the para position. This functional group imparts unique electronic and steric properties, making it attractive for various synthetic transformations.

The physical properties, such as its typical off-white powder appearance and relatively high boiling point (224.3 u00b1 35.0 u00b0C at 760 mmHg), are important considerations for handling and processing. Its density of approximately 1.2 g/cmu00b3 and a flash point around 89.4 u00b1 25.9 u00b0C also inform safe laboratory and industrial practices.

Applications in Organic Synthesis

The primary application for 4-(Difluoromethyl)benzonitrile lies in its role as an intermediate for organic synthesis. It serves as a crucial starting material or building block in the:

  • Pharmaceutical industry: The difluoromethyl group is often incorporated into drug molecules to modify their metabolic stability, lipophilicity, and binding affinity.
  • Agrochemical sector: Similar to pharmaceuticals, this intermediate can be used to develop new pesticides, herbicides, and fungicides with enhanced efficacy and specific modes of action.
  • Materials science: Its structure can be leveraged in the creation of specialty polymers, liquid crystals, and other advanced materials where fluorination confers desirable properties.

The demand for high-purity intermediates like ours ensures that synthetic pathways proceed efficiently with minimal by-product formation.

Reliable Sourcing from a Trusted Manufacturer

For businesses seeking to buy 4-(Difluoromethyl)benzonitrile, securing a consistent and high-quality supply is critical. As a dedicated manufacturer and supplier in China, we specialize in providing this compound with rigorous quality control. Our production processes are geared towards ensuring an assay of u226598.0% and low moisture content (u22640.5%). We offer flexible packaging options, typically 25 kg drums, to meet diverse industrial needs.

When you need to purchase this key intermediate, reaching out to a reputable manufacturer for a quote ensures you are getting genuine product quality at a competitive price. We are committed to supporting your research and development efforts by providing a dependable source for 4-(Difluoromethyl)benzonitrile.