The Chemistry Behind 5-Chloro-3-hydroxyisothiazole: Properties and Uses
Understanding the fundamental chemistry of critical intermediates is vital for any successful synthesis project. 5-Chloro-3-hydroxyisothiazole (CAS: 25629-58-7) is a significant heterocyclic compound widely utilized in the pharmaceutical industry. This article explores its key chemical properties and its role as a valuable building block. For those looking to buy this essential chemical, knowing its characteristics helps in making informed procurement decisions, especially when sourcing from a manufacturer.
The molecular formula of 5-Chloro-3-hydroxyisothiazole is C3H2ClNOS, with a molecular weight of 135.57200. It typically presents as a white powder, indicating its solid state at room temperature. Its reported melting point of 96-97 °C further confirms its solid nature. The predicted density is 1.62±0.1 g/cm³. These physical properties are crucial for handling, storage, and reaction planning. Maintaining a purity level of 97%+ is standard for this intermediate, ensuring its efficacy in downstream synthesis.
The primary utility of 5-Chloro-3-hydroxyisothiazole lies in its application as a pharmaceutical intermediate and in broader fine chemical manufacturing. Its heterocyclic structure, featuring a chlorine atom and a hydroxyl group on an isothiazole ring, provides reactive sites that are highly sought after in organic synthesis. It serves as a key precursor for creating more complex molecules, which are often the active components in pharmaceutical drugs.
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Whether you are a research scientist developing new APIs or a procurement manager optimizing your supply chain, understanding the properties and applications of 5-Chloro-3-hydroxyisothiazole is key. We invite you to explore our offerings and contact us to discuss your specific requirements for this crucial chemical intermediate.
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