Understanding the chemical nuances of essential biochemicals is crucial for any researcher or manufacturer working with them. N-alpha-Boc-L-Arginine (CAS 13726-76-6) is a prime example of such a compound, widely utilized due to its specific structural features and reactivity. As a prominent manufacturer and supplier of fine chemicals, we delve into the chemistry that makes this amino acid derivative so valuable.

The structure of N-alpha-Boc-L-Arginine features the amino acid L-arginine with a tert-butoxycarbonyl (Boc) group attached to the alpha-amino nitrogen. This Boc protection is central to its utility. The Boc group renders the amine less nucleophilic and prevents it from reacting during certain chemical transformations, particularly in peptide synthesis where selective reactions are paramount. Its molecular formula, C11H22N4O4, and molecular weight of approximately 274.32 g/mol, are key identifiers for procurement and synthesis planning. The presence of the guanidino group in the side chain of arginine also imparts unique properties and potential for interactions.

When considering the synthesis of N-alpha-Boc-L-Arginine, standard protection protocols are typically employed. These often involve reacting L-arginine with di-tert-butyl dicarbonate (Boc anhydride) in a suitable solvent system, often under mild basic conditions. The efficiency and yield of this reaction are critical for manufacturers aiming to provide high-quality products at competitive prices. Ensuring minimal racemization and high purity is a hallmark of a skilled chemical manufacturer.

In terms of physical properties, N-alpha-Boc-L-Arginine is typically a white to off-white solid. Its melting point, commonly cited in the range of 117-119°C, is a standard quality control parameter. For optimal long-term storage, it is recommended to keep the material sealed and dry, preferably at low temperatures (around 0°C or -20°C depending on the supplier's recommendation) to maintain its chemical stability and prevent degradation. Solubility in common solvents like DMF, DMSO, and ethanol is also important for its application in various reaction media.

For researchers and procurement specialists looking to buy Boc-L-Arginine, understanding these chemical properties ensures that they are selecting the right grade for their intended use. Whether for complex peptide synthesis, as a pharmaceutical intermediate, or for specific biochemical assays, knowing the nuances of the compound is key. Our role as a manufacturer is to provide not just the chemical, but also the assurance of its quality and handling requirements.

We are committed to supplying N-alpha-Boc-L-Arginine (CAS 13726-76-6) that meets the highest chemical standards. For inquiries about pricing, bulk orders, or specific technical details, please do not hesitate to contact our expert team. We are your reliable partner for high-quality amino acid derivatives.