The Chemistry Behind Boc-L-Lys(Z)-OH: Applications in Research
Boc-L-Lys(Z)-OH (CAS 2389-45-9) is a specialized amino acid derivative that plays a pivotal role in various chemical and biochemical research applications, most notably in peptide synthesis. Its unique chemical structure, featuring protective groups on both the alpha and epsilon amino positions of lysine, makes it an essential reagent for controlled molecular construction.
The tert-butoxycarbonyl (Boc) group on the alpha-amino position is acid-labile, meaning it can be selectively removed under acidic conditions. This characteristic is fundamental to its use in Solid Phase Peptide Synthesis (SPPS), allowing for the stepwise addition of amino acids to a growing peptide chain. Similarly, the benzyloxycarbonyl (Z or Cbz) group on the epsilon-amino position of the lysine side chain offers orthogonal protection, meaning it can be removed under different conditions (typically hydrogenolysis), providing further control over synthetic strategies.
Researchers often search for 'Boc-L-Lys(Z)-OH for peptide synthesis' or 'CAS 2389-45-9 manufacturer' when looking to procure this compound for their projects. The availability of high-purity material, often with an assay of ≥98.0%, is critical for ensuring the success of delicate synthetic procedures. A reliable Boc-L-Lys(Z)-OH supplier, particularly one based in China, can offer competitive Boc-L-Lys(Z)-OH price points, making advanced research more accessible.
Beyond SPPS, this compound can also be a valuable intermediate in the synthesis of peptidomimetics, modified peptides, and other complex organic molecules. Its applications extend to areas such as bioconjugation for targeted drug delivery, protein engineering, and the development of diagnostic assays. The precise chemical reactivity and stability afforded by the Boc and Z protecting groups are what make it so versatile.
For scientists and procurement specialists, identifying a trusted Boc-L-Lys(Z)-OH supplier is key to advancing research. Ensuring the product meets stringent purity standards and is available in appropriate quantities allows for seamless integration into experimental workflows. Whether you are synthesizing a complex peptide for drug discovery or developing novel biochemical tools, high-quality Boc-L-Lys(Z)-OH is a non-negotiable component.
Perspectives & Insights
Bio Analyst 88
“Its applications extend to areas such as bioconjugation for targeted drug delivery, protein engineering, and the development of diagnostic assays.”
Nano Seeker Pro
“The precise chemical reactivity and stability afforded by the Boc and Z protecting groups are what make it so versatile.”
Data Reader 7
“For scientists and procurement specialists, identifying a trusted Boc-L-Lys(Z)-OH supplier is key to advancing research.”