The Chemistry Behind D-2-Chlorophenylalanine: A Supplier's Perspective
As a leading manufacturer and supplier, we often receive inquiries about the fundamental chemistry behind the products we offer, especially for specialized compounds like D-2-Chlorophenylalanine (CAS: 80126-50-7). Understanding its molecular structure, synthesis, and key properties is essential for B2B customers in the pharmaceutical and fine chemical industries who rely on its unique capabilities.
D-2-Chlorophenylalanine is an alpha-amino acid derivative. Its core structure is that of phenylalanine, but with two critical modifications: the chlorine atom substitution at the phenyl ring's 2-position (ortho-chloro) and the stereochemical configuration at the alpha-carbon being 'D' (dextrorotatory) rather than the 'L' (levorotatory) found in most natural proteins. This specific configuration and halogenation are not accidental; they are deliberately incorporated to impart specific chemical and biological properties to molecules synthesized using it.
From a chemical perspective, the chlorine atom is electron-withdrawing, which can influence the reactivity of the phenyl ring and potentially affect hydrogen bonding or other intermolecular interactions. The D-chirality is particularly important for applications in peptide synthesis, where the incorporation of D-amino acids can alter a peptide's conformation, resistance to enzymatic degradation, and interaction with biological targets. Our commitment as a manufacturer is to produce this compound with high purity, typically 97% or greater, ensuring that these specific chiral and chemical properties are maintained without significant contamination from other isomers or impurities.
The applications for D-2-Chlorophenylalanine are rooted in its chemical distinctiveness. It serves as a vital building block in solid-phase peptide synthesis (SPPS) and solution-phase synthesis, enabling the creation of custom peptides with specific properties for research and therapeutic development. Furthermore, it is a valuable pharmaceutical intermediate, used by drug manufacturers in the synthesis of active pharmaceutical ingredients (APIs) where its unique structural elements are required. Procurement managers looking to buy D-2-Chlorophenylalanine will find that sourcing from an experienced manufacturer like ourselves ensures product consistency and competitive pricing.
We invite researchers, formulators, and procurement specialists to explore the chemical advantages of D-2-Chlorophenylalanine. As a dedicated supplier, we are ready to provide detailed specifications, samples, and quotes to meet your specific project needs. Trust us for your high-purity D-2-Chlorophenylalanine supply requirements.
Perspectives & Insights
Data Seeker X
“From a chemical perspective, the chlorine atom is electron-withdrawing, which can influence the reactivity of the phenyl ring and potentially affect hydrogen bonding or other intermolecular interactions.”
Chem Reader AI
“The D-chirality is particularly important for applications in peptide synthesis, where the incorporation of D-amino acids can alter a peptide's conformation, resistance to enzymatic degradation, and interaction with biological targets.”
Agile Vision 2025
“Our commitment as a manufacturer is to produce this compound with high purity, typically 97% or greater, ensuring that these specific chiral and chemical properties are maintained without significant contamination from other isomers or impurities.”