The Chemistry Behind D-2-Chlorophenylalanine: A Supplier's Perspective
As a leading manufacturer and supplier, we often receive inquiries about the fundamental chemistry behind the products we offer, especially for specialized compounds like D-2-Chlorophenylalanine (CAS: 80126-50-7). Understanding its molecular structure, synthesis, and key properties is essential for B2B customers in the pharmaceutical and fine chemical industries who rely on its unique capabilities.
D-2-Chlorophenylalanine is an alpha-amino acid derivative. Its core structure is that of phenylalanine, but with two critical modifications: the chlorine atom substitution at the phenyl ring's 2-position (ortho-chloro) and the stereochemical configuration at the alpha-carbon being 'D' (dextrorotatory) rather than the 'L' (levorotatory) found in most natural proteins. This specific configuration and halogenation are not accidental; they are deliberately incorporated to impart specific chemical and biological properties to molecules synthesized using it.
From a chemical perspective, the chlorine atom is electron-withdrawing, which can influence the reactivity of the phenyl ring and potentially affect hydrogen bonding or other intermolecular interactions. The D-chirality is particularly important for applications in peptide synthesis, where the incorporation of D-amino acids can alter a peptide's conformation, resistance to enzymatic degradation, and interaction with biological targets. Our commitment as a manufacturer is to produce this compound with high purity, typically 97% or greater, ensuring that these specific chiral and chemical properties are maintained without significant contamination from other isomers or impurities.
The applications for D-2-Chlorophenylalanine are rooted in its chemical distinctiveness. It serves as a vital building block in solid-phase peptide synthesis (SPPS) and solution-phase synthesis, enabling the creation of custom peptides with specific properties for research and therapeutic development. Furthermore, it is a valuable pharmaceutical intermediate, used by drug manufacturers in the synthesis of active pharmaceutical ingredients (APIs) where its unique structural elements are required. Procurement managers looking to buy D-2-Chlorophenylalanine will find that sourcing from an experienced manufacturer like ourselves ensures product consistency and competitive pricing.
We invite researchers, formulators, and procurement specialists to explore the chemical advantages of D-2-Chlorophenylalanine. As a dedicated supplier, we are ready to provide detailed specifications, samples, and quotes to meet your specific project needs. Trust us for your high-purity D-2-Chlorophenylalanine supply requirements.
Perspectives & Insights
Quantum Pioneer 24
“As a leading manufacturer and supplier, we often receive inquiries about the fundamental chemistry behind the products we offer, especially for specialized compounds like D-2-Chlorophenylalanine (CAS: 80126-50-7).”
Bio Explorer X
“Understanding its molecular structure, synthesis, and key properties is essential for B2B customers in the pharmaceutical and fine chemical industries who rely on its unique capabilities.”
Nano Catalyst AI
“This specific configuration and halogenation are not accidental; they are deliberately incorporated to impart specific chemical and biological properties to molecules synthesized using it.”