The Chemistry Behind D-2-Phenylglycine: From Synthesis to Application
D-2-Phenylglycine (CAS 875-74-1) is a molecule of significant interest in organic chemistry, particularly due to its pivotal role in pharmaceutical synthesis. This chiral amino acid derivative, appearing as a white or off-white crystal powder, serves as a crucial intermediate in the production of semi-synthetic antibiotics. Its chemical structure and properties are key to its efficacy in creating complex pharmaceutical compounds.
The synthesis of D-2-Phenylglycine involves specific chemical reactions that yield a product with high purity, essential for its downstream applications. Manufacturers focus on achieving precise stereochemistry and minimizing impurities, often targeting an assay of 98% or higher. The physical properties, such as a high melting point (302°C dec.) and limited water solubility (0.3g/100mL), are critical parameters that chemists consider when incorporating it into synthesis pathways. For those looking to buy D-2-Phenylglycine, understanding these chemical nuances helps in selecting the appropriate grade and supplier.
The primary application of D-2-Phenylglycine lies in its function as a side-chain intermediate for broad-spectrum antibiotics like Cephalexin and Cefradine, as well as various penicillin derivatives. This makes it a cornerstone for companies involved in anti-infective drug manufacturing. A reliable D-2-Phenylglycine manufacturer is expected to adhere to strict quality control measures, ensuring the integrity of the chemical structure and purity. Sourcing from China offers potential cost advantages, with competitive D-2-Phenylglycine prices available for bulk orders.
Beyond its role in established antibiotic production, D-2-Phenylglycine is also explored in research for developing new chiral drugs and fine chemical synthesis. As the pharmaceutical industry continues to innovate, the demand for high-quality intermediates like D-2-Phenylglycine is likely to remain strong. Therefore, identifying a trustworthy manufacturer or supplier is a strategic imperative for any research or manufacturing facility.
Perspectives & Insights
Future Origin 2025
“A reliable D-2-Phenylglycine manufacturer is expected to adhere to strict quality control measures, ensuring the integrity of the chemical structure and purity.”
Core Analyst 01
“Sourcing from China offers potential cost advantages, with competitive D-2-Phenylglycine prices available for bulk orders.”
Silicon Seeker One
“Beyond its role in established antibiotic production, D-2-Phenylglycine is also explored in research for developing new chiral drugs and fine chemical synthesis.”