The Chemistry Behind D-2-Phenylglycine: From Synthesis to Application
D-2-Phenylglycine (CAS 875-74-1) is a molecule of significant interest in organic chemistry, particularly due to its pivotal role in pharmaceutical synthesis. This chiral amino acid derivative, appearing as a white or off-white crystal powder, serves as a crucial intermediate in the production of semi-synthetic antibiotics. Its chemical structure and properties are key to its efficacy in creating complex pharmaceutical compounds.
The synthesis of D-2-Phenylglycine involves specific chemical reactions that yield a product with high purity, essential for its downstream applications. Manufacturers focus on achieving precise stereochemistry and minimizing impurities, often targeting an assay of 98% or higher. The physical properties, such as a high melting point (302°C dec.) and limited water solubility (0.3g/100mL), are critical parameters that chemists consider when incorporating it into synthesis pathways. For those looking to buy D-2-Phenylglycine, understanding these chemical nuances helps in selecting the appropriate grade and supplier.
The primary application of D-2-Phenylglycine lies in its function as a side-chain intermediate for broad-spectrum antibiotics like Cephalexin and Cefradine, as well as various penicillin derivatives. This makes it a cornerstone for companies involved in anti-infective drug manufacturing. A reliable D-2-Phenylglycine manufacturer is expected to adhere to strict quality control measures, ensuring the integrity of the chemical structure and purity. Sourcing from China offers potential cost advantages, with competitive D-2-Phenylglycine prices available for bulk orders.
Beyond its role in established antibiotic production, D-2-Phenylglycine is also explored in research for developing new chiral drugs and fine chemical synthesis. As the pharmaceutical industry continues to innovate, the demand for high-quality intermediates like D-2-Phenylglycine is likely to remain strong. Therefore, identifying a trustworthy manufacturer or supplier is a strategic imperative for any research or manufacturing facility.
Perspectives & Insights
Silicon Analyst 88
“3g/100mL), are critical parameters that chemists consider when incorporating it into synthesis pathways.”
Quantum Seeker Pro
“For those looking to buy D-2-Phenylglycine, understanding these chemical nuances helps in selecting the appropriate grade and supplier.”
Bio Reader 7
“The primary application of D-2-Phenylglycine lies in its function as a side-chain intermediate for broad-spectrum antibiotics like Cephalexin and Cefradine, as well as various penicillin derivatives.”